Maternal-Fetal Medicine — Flashcards

Flashcard 41: _____ pregnancies rupture at an early stage.

Answer: Isthmic

Extra: The isthmus is the narrowest part of the fallopian tube and has the least distensibility, leading to early rupture (typically 6-8 weeks).

Flashcard 42: Placental abruption typically presents with abrupt, _____ third trimester bleeding

Answer: painful

Flashcard 43: Increased nuchal translucency measured between _____ weeks is associated with adverse pregnancy outcomes like fetal demise, cardiac abnormalities, and other genetic syndromes, even if the karyotype is normal.

Answer: 11 and 13

Extra: Increased nuchal translucency (NT) is a marker for aneuploidy (e.g., Trisomy 21). However, if the karyotype is normal, an increased NT still carries a higher risk for structural anomalies (especially congenital heart defects), skeletal dysplasias, and certain genetic syndromes (e.g., Noonan syndrome). The optimal window for measurement is 11 weeks 0 days to 13 weeks 6 days (CRL 45-84 mm).

Flashcard 44: _____ -coagulable states are often complicated by recurrent pregnancy loss (women)

Answer: Hyper

Flashcard 45: In a patient of cardiac disease, Heparin (unfractionated or LMWH) is restarted _____ hours after vaginal delivery and 24 hours after cesarean section.

Answer: 6

Flashcard 46: Protocol for Rh isoimmunization: If **MCA-PSV** is _____ than 1.5 deliver at 37 completed weeks

Answer: less

Extra: In Rh isoimmunization, the **Middle Cerebral Artery Peak Systolic Velocity (MCA-PSV)** is monitored to detect fetal anemia. - **< 1.5 MoM**: Suggests mild or no anemia. If it remains below this threshold, delivery is typically recommended at **37–38 weeks**. - **≥ 1.5 MoM**: Suggests severe fetal anemia; requires further investigation (cordocentesis) and potential intrauterine transfusion (IUT). Note: The term "Critical Titer" refers to antibody levels (e.g., 1:16), not the MoM value.

Flashcard 47: Spontaneous abortion is most often due to _____ anomalies, especially trisomy 16

Answer: chromosomal

Flashcard 48: Hematocrit of _____% and hemoglobin of 10 g% is necessary for expectant management of placenta previa

Answer: 30

Flashcard 49: Pregnant women taking _____ have a 1-2% risk of delivering a baby with spina bifida.

Answer: sodium valproate

Flashcard 50: According to Pritchard's regimen, the maintenance dose of MgSo4 in pre-eclampsia is _____ IM 4 hourly in alternate buttocks.

Answer: 5 g (50%)