Virology — Flashcards

Flashcard 111: Epstein-Barr virus binds to _____ (the C3d receptor, also known as CR2) on B-cells, causing B-cell proliferation.

Answer: CD21

Extra: EBV binds to CD21 (also known as Complement Receptor 2 / CR2 and the C3d receptor) on B-cells. This leads to B-cell proliferation and the production of heterophile antibodies.

Flashcard 112: The _____ virus families include bunyavirus, orthomyxovirus, arenavirus, and reovirus

Answer: segmented

Flashcard 113: Bunyaviruses have _____ circular segments

Answer: 3

Flashcard 114: _____ virus binds to nicotinic ACh receptors in the post-synaptic membrane of the neuromuscular junction

Answer: Rabies

Flashcard 115: _____ is the only DNA virus that completely replicates in the cytoplasm

Answer: Poxvirus

Flashcard 116: Which envelope protein on HIV functions to allow attachment to host CD4+ T cells?_____

Answer: gp120

Flashcard 117: The two most common shapes of viral capsids are _____ and helical

Answer: icosahedral

Flashcard 118: _____ are the only DNA viruses without icosahedral symmetry, and instead have a "box" or "brick" shape.

Answer: Poxviruses

Flashcard 119: _____ are a class of RNA viruses that obtain their envelope from host cell's golgi apparatus (golgi body complex)

Answer: Bunyaviruses

Flashcard 120: Coronavirus has _____ or petal shaped peplomers on its surface

Answer: club