Virology — Flashcards

Flashcard 101: In _____ HIV infection, HIV gains entry into macrophages via binding to CD4 plus the coreceptor CCR5

Answer: early

Flashcard 102: Upon entry into the cell _____, HBV DNA-polymerase completes the partially dsDNA

Answer: nucleus

Flashcard 103: Antigenic variation can be due to antigenic _____ or antigenic shift

Answer: drift

Flashcard 104: _____ are a class of viruses that have arthropod vectors

Answer: Arboviruses

Flashcard 105: The _____ gene of HIV encodes p24 and p17

Answer: gag

Flashcard 106: _____ stranded RNA viruses use RNA dependent RNA polymerase during genome replication

Answer: Negative

Flashcard 107: The new UK variant of SARS-CoV-2 (termed as VOC-202012/01) is defined by multiple _____ mutations leading to increased transmissibility

Answer: spike protein

Flashcard 108: HHV-_____ induces VEGF, resulting in proliferation of vascular endothelial cells

Answer: 8

Flashcard 109: Epstein-Barr virus binds to _____ (the C3d receptor, also known as CR2) on B-cells, causing B-cell proliferation.

Answer: CD21

Extra: EBV binds to CD21 (also known as Complement Receptor 2 / CR2 and the C3d receptor) on B-cells. This leads to B-cell proliferation and the production of heterophile antibodies.

Flashcard 110: Antigenic variation of influenza viruses occurs with changes to viral _____ and neuraminidase (NA)

Answer: hemagglutinin (HA)