New Antimicrobial Development — Flashcards

Flashcard 1: Resistance to cephalosporins and aztreonam is typically accomplished by _____ that are encoded on plasmids

Answer: Extended-Spectrum Beta-Lactamases (ESBL)

Flashcard 2: The disc diffusion method for antibiotic susceptibility testing is applied in the _____ method.

Answer: Kirby Bauer

Flashcard 3: Gene Xpert identifies mutations in the _____ gene to detect rifampicin resistance

Answer: rpoB

Flashcard 4: Burkholderia cepacia is resistant to _____ gen. cephalosporins, aminoglycosides, polymyxin and carboxypenicillins

Answer: first and second

Flashcard 5: _____ resistance occurs in Enterococcus spp. (VRE) via amino acid modification of D-Ala-D-Ala to D-Ala-D-Lac.

Answer: Vancomycin

Flashcard 6: _____ genes are responsible for FQ resistance

Answer: gyrA and gyrB

Extra: 

Flashcard 7: _____ gene from vancomycin-resistant Enterococcus to S. aureus is an example of transposition.

Answer: VanA

Flashcard 8: Community acquired MRSA is _____drug resistant and more virulent

Answer: mono

Flashcard 9: Resistance in MRSA is mediated by _____ gene which is coded on the chromosome

Answer: mecA

Flashcard 10: _____ agar is used in Kirby-Bauer s disc diffusion method of antibiotic sensitivity testing.

Answer: Mueller-Hinton