Oncology — Flashcards

Flashcard 21: In the International Prognostic Score (IPS) for Hodgkin lymphoma, what serum albumin level is considered a poor prognostic factor?

Answer: < 4 g/dL

Extra: The 7 International Prognostic Score (IPS) factors (Hasenclever index) for advanced Hodgkin lymphoma are: 1. Albumin < 4 g/dL 2. Hemoglobin < 10.5 g/dL 3. Male sex 4. Stage IV disease 5. Age ≥ 45 years 6. White cell count ≥ 15,000/mm³ 7. Lymphocyte count < 600/mm³ or < 8% of white cell count

Flashcard 22: _____ is a rare paraneoplastic syndrome which presents with hypophosphatemia, osteomalacia and renal phosphate wasting.

Answer: Tumor-induced osteomalacia (TIO)

Flashcard 23: _____ is being used as the neoadjuvant regimen of choice in patients with borderline resectable pancreatic cancer and good performance status who can tolerate this aggressive regimen.

Answer: FOLFIRINOX

Flashcard 24: In Hodgkin Lymphoma, what is the characteristic effect of alcohol consumption on involved lymph nodes?

Answer: Increases pain (Alcohol-induced pain)

Flashcard 25: Osimertinib, as a third-generation EGFR inhibitor is effective against NSCLC with _____ mutation

Answer: T790M

Flashcard 26: What is the prognosis of Mucinous Cystic Neoplasms (MCNs) of the pancreas?

Answer: Excellent (especially after surgical resection)

Extra: Mucinous cystic neoplasms (MCNs) are typically found in the body or tail of the pancreas in women and are characterized by 'ovarian-like' stroma. Unlike pancreatic ductal adenocarcinoma, MCNs have an excellent prognosis with a 5-year survival rate of >90% following complete surgical resection.

Flashcard 27: The anticoagulant of choice for the management of cancer-associated thromboembolism is _____

Answer: low-molecular-weight heparin (LMWH)

Flashcard 28: Pancreatic cancer has the highest association with which cancer syndrome?_____

Answer: Peutz Jeghers syndrome

Flashcard 29: Which chemotherapy regimen is traditionally used for both gastric and oesophageal carcinomas, and what does it consist of?

Answer: ECF (Epirubicin, Cisplatin, 5-Fluorouracil)

Flashcard 30: The first line rx for management of metastatic prostatic cancer is _____

Answer: hormone ablation