Weight Loss and Cachexia — Flashcards

Flashcard 1: According to the Van Nuys Prognostic Index (VNPI) for DCIS, what is the recommended management for a patient with a score of 7, 8, or 9?

Answer: Excision + Radiation therapy

Extra: The Van Nuys Prognostic Index (VNPI) is used to guide the management of Ductal Carcinoma In Situ (DCIS) based on the risk of local recurrence. **Parameters (scored 1-3 each):** 1. Tumor size 2. Margin width 3. Pathological classification (Nuclear grade & necrosis) 4. Age **Management based on score:** * **4, 5, 6:** Excision (Breast Conserving Surgery) alone * **7, 8, 9:** Excision + Radiation therapy * **10, 11, 12:** Mastectomy

Flashcard 2: _____ is a painful sustained erection lasting >4 hours

Answer: Ischemic priapism

Flashcard 3: Anemia is classified as _____ when the MCV > 100 fL

Answer: macrocytic

Flashcard 4: Mentzer index is defined as the quotient of _____

Answer: MCV/TRBC

Flashcard 5: If the Mentzer index is _____, the patient likely has iron deficiency anemia.

Answer: > 13

Flashcard 6: In the **two-tier (Modified) Well's Criteria** for Pulmonary Embolism, a score of _____ points indicates that PE is **likely** or "probable".

Answer: > 4

Extra: The Modified (Two-tier) Well's Criteria is used to clinicaly assess the probability of Pulmonary Embolism (PE): - **Score > 4**: PE Likely (Directly proceed to imaging, typically CT Pulmonary Angiography). - **Score ≤ 4**: PE Unlikely (Proceed to high-sensitivity D-dimer testing to rule out PE).

Flashcard 7: McArdle disease is associated with painful _____ that occur with strenuous exercise

Answer: muscle cramps

Flashcard 8: Vitamin _____ deficiency is characterized by sideroblastic anemia and peripheral neuropathy

Answer: B6

Flashcard 9: Vitamin _____ deficiency (rare) presents with dermatitis, enteritis, alopecia, and adrenal insufficiency

Answer: B5

Flashcard 10: Calf tenderness on direct pressure on calf, is seen in _____: Moses sign

Answer: DVT