Dermatitis and Eczema Indian Medical PG Flashcards - Medical Study Cards
Master Dermatitis and Eczema with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Dermatitis and Eczema Flashcard Deck - 10 Cards
Flashcard 11: What lesion is associated with chorea?
Answer: basal ganglia
Flashcard 12: What lesion is associated with intention tremor?
Answer: cerebellar lesion/dysfunction
Flashcard 13: dystonia
Answer: sustained involuntary muscle contractions
Flashcard 14: postural tremor
Answer: type of action tremor; vibratory tremor when holding a posture, exacerbated by intentional movement
Flashcard 15: coordination of trunk
Answer: medial cerebellum
Flashcard 16: What is the purpose of the CNS blood-brain barrier?
Answer: limits diffusion of blood components or solutes into CSF/CNS --> protection from infection and intoxication
Flashcard 17: What triplet is associated with Friedrich's ataxia?
Answer: GAA
mnemonic: X-Girlfriend's First Aid Helped Ace My Test
Flashcard 18: Genetic basis of Friedreich's ataxia?
Answer: Autosomal recessive, GAA triplet repeat disorder, FXN gene (Frataxin) expansion.
Extra: Friedreich Ataxia:
- Genetics: GAA repeat on Chromosome 9
- Clinical: Hypertrophic cardiomyopathy (most common cause of death), diabetes mellitus, kyphoscoliosis, pes cavus.
- Neuro: Cerebellar atrophry, degeneration of posterior columns and spinocerebellar tracts.
Mnemonic: X-Girlfriend's First Aid Helped Ace My Test (FXN gene, GAA repeat, Friedreich Ataxia, Myocardial involvement, Type 1 Diabetes).
Flashcard 19: What is the pathophysiology and cardinal clinical features of Parkinson's disease?
Answer: A degenerative disorder of the CNS characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNc).
Extra: - **Symptoms:** Resting tremor, rigidity, bradykinesia, postural instability (TRAP).
- **Pathology:** Lewy bodies (α-synuclein), depigmentation of SNc.
- **Neurochemistry:** Decreased dopamine in SNc.
- **Treatment Classes:**
- Dopamine precursor (Levodopa)
- Dopamine agonists (Pramipexole, Ropinirole)
- Increase dopamine release (Amantadine)
- Dopamine breakdown inhibitors (MAO-B inhibitors, COMT inhibitors)
- Antimuscarinics (Benztropine)
Flashcard 20: hemiballismus
Answer: sudden, wild flailing of limb or limbs on one side of body
Extra: Usually due to a lesion in the contralateral subthalamic nucleus (e.g., lacunar stroke).
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