Immunization and Vaccine-Preventable Diseases — Flashcards

Flashcard 31: ILR (ice-lined refrigerator) can maintain the cold chain for _____ hours without electricity (hold-over time).

Answer: 24-48

Extra: Hold-over time is the duration for which the temperature remains between +2°C to +8°C during power failure (provided the lid is not opened). • ILR: 24–48 hours • Cold box: 2–7 days • Vaccine carrier: 12–48 hours • Day carrier: 6–8 hours Note: ILR requires at least 8 hours of electricity supply in a 24-hour period to maintain the cold chain.

Flashcard 32: there should be atleast _____ of gap between PCV(pneumococcal conjugated vaccine) doses

Answer: 8 weeks

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Flashcard 33: The advantage of _____ vaccines over pure polysaccharide vaccines is that they can be given to children < 2 years of age.

Answer: conjugate

Extra: Polysaccharide vaccines are T-cell independent antigens and are poorly immunogenic in children < 2 years of age. Conjugate vaccines (e.g., Hib, PCV) link the polysaccharide to a protein carrier, inducing a T-cell dependent response that is effective in infants and young children.

Flashcard 34: disadvantage of freeze dried vaccine is _____

Answer: risk of contamination 

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Flashcard 35: Immunity from yellow fever vaccine starts from _____ and lasts for _____

Answer: 10 days

Extra: Yellow fever vaccine (17D strain) is a live attenuated vaccine. According to the International Health Regulations (WHO), a single dose provides lifelong protection. The international certificate of vaccination becomes valid 10 days after the date of vaccination and remains valid for the life of the person vaccinated.

Flashcard 36: shake test is done for which vaccines

Answer: PCV(pneumococcal conjugate) pentavalent basically for freeze sensitive vaccines AIIMS 18 MCQ

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Flashcard 37: _____ vaccine preventable diseases are included in intensified mission indradhanush 2.0

Answer: 12

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Flashcard 38: immunity from measles vaccine lasts till _____

Answer: lifetime

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Flashcard 39: WHO criteria for neonatal tetanus elimination is _____ per district

Answer: <1 case per 1000 live births

Flashcard 40: 1. Identify → _____ 2. Dose, Route and Schedule → _____

Answer: Japanese Encephalitis Vaccine

Extra: y