Protein Structure and Function — Flashcards

Prion disease arises with conversion to a _____ conformation, known as PrPsc

Prion proteins have two isoforms: _____ that causes disease and PrPc, the normal prion protein, found in human cells

The typical ratio of kappa to lambda immunoglobulin light chain phenotypes is _____:2

Collagen Synthesis: Following hydroxylation of proline and lysine, there is _____ of pro-α chain hydroxylysine residues

One normal type of hemoglobin is _____ which is composed of two alpha and two beta chains

While being packed into secretory granules, proteases cleave the _____ of proinsulin, yielding insulin

Sickle cell anemia occurs due to a point mutation that substitutes _____ (hydrophilic) with valine (hydrophobic)

There are four superfamilies of proteins namely _____, dynein, myosin, dynamins referred to as molecular motors.

Compounds that have the same chemical formula but different structures are called _____ of each other

Which amino acid does not participate in the formation of alpha helix?_____