Protein Structure and Function — Flashcards

Collagen Synthesis: Once in the extracellular space, cleavage of disulfide-rich terminal regions of procollagen by _____ forms the insoluble tropocollagen

Collagen Synthesis: After the collagen pro-alpha chains are synthesized, specific residues of the amino acids _____ and lysine are hydroxylated

_____ increase binding of thyroxine to thyroxine binding globulin

Hint: Hormone

Prion protein is normally expressed in CNS neurons in an _____ conformation, known as PrPc

The _____ of preproinsulin is cleaved while the peptide chains are being assembled, yielding proinsulin

Dystrophin normally anchors the muscle _____ to the extracellular matrix; primarily in skeletal and cardiac muscle

Formation of lysine-hydroxylysine cross-linkages (collagen synthesis) requires both _____ and the enzyme lysyl oxidase

In the golgi apparatus, peptide sequences are cleaved from the prohormone to form the _____, which is stored in secretory vesicles for later release

Each B cell produces light chains that are either _____ or lambda

The _____ family of hormones is derived from a single precursor, pro-opiomelanocortin (POMC)