Lipid Metabolism — Flashcards

Flashcard 151: Which prostaglandins are also known as primary prostaglandins?_____

Answer: PGD2, PGE2, and PGF2a

Flashcard 152: Triacylglycerol is synthesized in adipose tissue using _____

Answer: dihydroxyacetone phosphate

Flashcard 153: Which lipoprotein molecule has the least percentage of lipid content, with the highest protein content?_____

Answer: HDL

Flashcard 154: The common precursor in the biosynthesis of Triacylglycerols and Phosphoglycerols is _____

Answer: phosphatidate

Flashcard 155: What is the acyl group carrier of intermediates in fatty acid synthesis?_____

Answer: sulfhydryl group of the Fatty acid synthase

Flashcard 156: IDLs undergo hydrolysis in the _____ of the liver to form LDL

Answer: Sinusoids

Extra: This conversion is mediated by **hepatic lipase** (HL). While lipoprotein lipase (LPL) acts in the capillaries of peripheral tissues (like adipose and muscle), HL acts specifically on the endothelial surface of the **hepatic sinusoids** to convert IDL to LDL.

Flashcard 157: Free fatty acids are transported in the blood bound to _____.

Answer: albumin

Flashcard 158: What enzyme catalyzes the final step (thiolysis) of beta-oxidation of fatty acids?

Answer: Thiolase (3-ketoacyl-CoA thiolase)

Flashcard 159: The most common form of lipid accumulation is _____

Answer: triglycerides

Flashcard 160: Gallstone chemistry most commonly seen is crystalline cholesterol _____hydrate.

Answer: mono