Lipid Metabolism — Flashcards

Flashcard 141: Deficiency of apolipoprotein _____ can be a risk factor development of acute pancreatitis

Answer: C-II

Flashcard 142: Which lipoxygenase is commonly seen in neutrophils?_____

Answer: 5-lipoxygenase

Flashcard 143: What are the Secondary bile acids?_____

Answer: Deoxycholic acid and lithocholic acid

Flashcard 144: The enzyme **glycerol kinase**, required for the activation and metabolism of glycerol, is notably **absent** in which tissue?

Answer: Adipose tissue

Extra: Glycerol kinase is the enzyme responsible for phosphorylating glycerol to glycerol-3-phosphate. It is present in the liver, kidneys, and intestines but is notably absent in adipose tissue (and muscle). Because adipocytes lack this enzyme, the glycerol released during the breakdown of triacylglycerols (lipolysis) cannot be reused within the adipose tissue for re-esterification; instead, it is released into the bloodstream and transported to the liver.

Flashcard 145: _____ is a primary ketone body.

Answer: Acetoacetate

Flashcard 146: Which fatty acids are known to possess anti-inflammatory activities?

Answer: Omega-3 fatty acids

Flashcard 147: Apo A-II _____ lipoprotein lipase.

Answer: inhibits (activates/inhibits)

Flashcard 148: Arachidonic acid is a semi-essential fatty acid since it can be derived from _____ acid.

Answer: Linoleic

Flashcard 149: What is the most active carbon atom donor in fatty acid synthesis?_____

Answer: Malonyl-coA

Flashcard 150: Which organ pair can synthesize the whole range of COX products?_____

Answer: Lung and spleen