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Designed for USMLE Step 1, Step 2 CK, and Step 3. Oncourse understands how you learn, builds on your strengths, and turns your effort into confidence.

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INTERNAL MEDICINE · BLOCK 2
Question 14 of 40
Next best step1:24
A 58-year-old man has had crushing chest pain for 40 minutes. ECG shows ST elevation in leads II, III, and aVF. The nearest PCI-capable hospital is 30 minutes away.
Hint: Find the diagnosis first, then ask how fast reperfusion can happen.(B) Inferior STEMI with PCI reachable within 120 minutes: aspirin, then primary PCI.(A) Lytics are for when PCI can't happen within 120 minutes.
What is the most appropriate next step in management?
AAlteplase in the emergency department
BAspirin and transfer for primary PCI
CCT angiography of the chest
DRepeat troponin in 3 hours
INTERNAL MEDICINE · BLOCK 2
Question 14 of 40
1:24
A 58-year-old man has had crushing chest pain for 40 minutes. ECG shows ST elevation in leads II, III, and aVF. The nearest PCI-capable hospital is 30 minutes away.
What is the most appropriate next step in management?
AAlteplase in the emergency department
BAspirin and transfer for primary PCI
CCT angiography of the chest
DRepeat troponin in 3 hours
Hint: Find the diagnosis first, then ask how fast reperfusion can happen.(B) Inferior STEMI with PCI reachable within 120 minutes: aspirin, then primary PCI.

Adaptive Question Bank

Adaptive quizzes across all subjects with interactive and personalized explanations.

BIOCHEMISTRY · GLYCOLYSIS12 due
QUESTIONRate-limiting enzyme of glycolysis?
ANSWERPhosphofructokinase-1 (PFK-1)
AgainHardGoodEasy
Back in 3 days · spaced repetition

High-Yield Flashcards

Practice spaced repetition with high-yield flashcards auto-resurfaced at your forgetting point.

Biochemistry › Amino acids
Catecholamine synthesis
Tyrosine
L-DOPA
Dopamine
Norepinephrine → Epinephrine
Quick check: 2 of 2

Interactive Lessons

Master high-yield concepts through interactive lessons packed with flowcharts, visuals, and tables designed for active recall.

Rezzy, the Oncourse AI study mate

With AI That Adapts to Your Pace & Style

Everything personalized to your pace and learning style, with Rezzy, your AI study mate.

9:41
Pharmacology
Why do ACE inhibitors cause a dry cough?
It's the bradykinin

ACE doesn't only make angiotensin II. It also breaks down bradykinin.

BradykininACEInactiveACE-Ibuilds upAirway irritationDry cough

ARBs act at the AT₁ receptor and spare bradykinin, so they're the usual switch.

What should I switch to?
Quiz me on this
Ask Rezzy anything
Why it matters
Knowing the mechanism answers the side-effect question and the switch question.

Everything Tough, Made Simple & Fun

Beyond just boring MCQs, solve Fill in the Blanks, Match the Following, and more.

STEP 2 CK READINESS
Block done · 31 / 40▲ 5 this week
61OUT OF 1004 of 10 specialties ready
Knowledge18 / 25
Coverage16 / 25
Exam Instinct13 / 25
Application12 / 25
Internal Medicine81Strong
OB/GYN54Developing
Psychiatry62Developing
STEP 2 CK READINESS
Block done · 31 / 40▲ 5 this week
61OUT OF 100
Knowledge18 / 25
Coverage16 / 25
Exam Instinct13 / 25
Application12 / 25
4 of 10 specialties ready
Internal Medicine81Exam ready
OB/GYN54Developing
Psychiatry62Developing

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Practice That Feels Like a Game

Two quick games built on high-yield medicine. Play one between study sessions to keep concepts fresh and find out what you haven't locked in yet.

Probe:Sharpen Your Diagnostic Reasoning

Dr. Holmes reads out one clue at a time and you say your answer out loud. The fewer clues you need, the better you know it.

1
CLUE 1
A harsh systolic murmur at the left sternal border.
CLUE 2
The child squats to ease cyanotic spells.
Dr. Holmes
Clue one. A harsh systolic murmur at the left sternal border.
Dr. Holmes is speaking…

Synapses:Find the Four Hidden Groups

Sixteen drugs, four hidden groups. Link the ones that belong together before your lifelines run out.

Create groups of 4!
Test your USMLE knowledge
00:08
LosartanAtenololEnalaprilAmlodipine
MetoprololValsartanRamiprilVerapamil
NifedipineEsmololIrbesartanCaptopril
LisinoprilDiltiazemNadololOlmesartan
LIFELINES
RESETCHECK
Perfect guess! Wohoo! 🎉

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Dr. MahekStep 2 CK · 260+

During residency, there were only a handful of questions available for my weakest topics while preparing for Step 2 CK. Oncourse opened the horizons of doing as many questions as I want and that too in an interactive way!

USMLE
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BeccaUS MD student · MS1

As a US MD student Oncourse has combined all of the resources into one amazing efficient resource. Rezzy helps me break down the hardest concepts and has made my studying 10x better. It's a life saver.

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Genuinely impressive platform for med students, there's no app like it right now! Especially the games like Image Rush & Clinical Rounds!

USMLE

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Prices in USD. Every plan includes Step 1, Step 2 CK, and Step 3.

Frequently asked questions

Does one subscription cover all three Steps?

Yes. One plan covers Step 1, Step 2 CK, and Step 3.

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Rezzy, the Oncourse AI study mate

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Oncourse is an independent exam-preparation product and is not affiliated with or endorsed by the FSMB or NBME. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME).