Delusional disorder Practice Questions

Question 1

A 55-year-old male was picked up by police in the public library for harassing the patrons and for public nudity. He displayed disorganized speech and believed that the books were the only way to his salvation. Identification was found on the man and his sister was called to provide more information. She described that he recently lost his house and got divorced within the same week although he seemed fine three days ago. The man was sedated with diazepam and chlorpromazine because he was very agitated. His labs returned normal and within three days, he appeared normal, had no recollection of the past several days, and discussed in detail how stressful the past two weeks of his life were. He was discharged the next day. Which of the following is the most appropriate diagnosis for this male?

Accepted Answer

Brief psychotic disorder

Answer

Schizotypal personality disorder

Answer

Schizophreniform disorder

Answer

Schizophrenia

Answer

Schizoid personality disorder

Question 2

A 45-year-old obese man is evaluated in a locked psychiatric facility. He was admitted to the unit after he was caught running through traffic naked while tearing out his hair. His urine toxicology screening was negative for illicit substances and after careful evaluation and additional history, provided by his parents, he was diagnosed with schizophrenia and was treated with aripiprazole. His symptoms did not improve after several dosage adjustments and he was placed on haloperidol, but this left him too lethargic and slow and he was placed on loxapine. After several dosage adjustments today, he is still quite confused. He describes giant spiders and robots that torture him in his room. He describes an incessant voice screaming at him to run away. He also strongly dislikes his current medication and would like to try something else. Which of the following is indicated in this patient?

Accepted Answer

Clozapine

Answer

Haloperidol

Answer

Olanzapine

Answer

Chlorpromazine

Answer

Fluphenazine

Question 3

A 23-year-old man is brought to the emergency department by his girlfriend because of acute agitation and bizarre behavior. The girlfriend reports that, over the past 3 months, the patient has become withdrawn and stopped pursuing hobbies that he used to enjoy. One month ago, he lost his job because he stopped going to work. During this time, he has barely left his apartment because he believes that the FBI is spying on him and controlling his mind. He used to smoke marijuana occasionally in high school but quit 5 years ago. Physical and neurologic examinations show no abnormalities. On mental status examination, he is confused and suspicious with marked psychomotor agitation. His speech is disorganized and his affect is labile. Which of the following is the most likely diagnosis?

Accepted Answer

Schizophreniform disorder

Answer

Schizoid personality disorder

Answer

Delusional disorder

Answer

Schizoaffective disorder

Answer

Brief psychotic disorder

Question 4

Two dizygotic twins present to the university clinic because they believe they are being poisoned through the school's cafeteria food. They have brought these concerns up in the past, but no other students or cafeteria staff support this belief. Both of them are average students with strong and weak subject areas as demonstrated by their course grade-books. They have no known medical conditions and are not known to abuse illicit substances. Which statement best describes the condition these patients have?

Accepted Answer

Can affect two or more closely related individuals.

Answer

A trial separation is likely to worsen symptoms.

Answer

The disorder is its own disease entity in DSM-5.

Answer

Antipsychotic medications are rarely beneficial.

Answer

Cognitive behavioral therapy is a good first-line.

Question 5

A 22-year-old man is brought to the emergency department by his father because he is having bizarre thoughts. The patient says that he is being haunted by aliens from outer space. The father is worried as his son has had these symptoms for the past 7 months and lately, it seems to be getting worse. He has become more self-obsessed and does not seem to have any interest in his favorite activities. He has no plans to harm himself or others but spends a lot of time and energy building ‘defenses’ in and around his room as he is absolutely sure that aliens will come to get him soon. His blood pressure is 121/79 mm Hg, pulse 86/min, respiratory rate 15/min, temperature 36.8°C (98.2°F). Which of the following is correct regarding the patient’s symptoms?

Accepted Answer

He has a fixed false belief.

Answer

It would benefit from psychosurgery.

Answer

It is best treated with cognitive behavioral therapy alone.

Answer

It is a negative symptom.

Answer

It falls under the disorganized thinking domain.

Question 6

A 34-year-old man presents to the behavioral health clinic for an evaluation after seeing animal-shaped clouds in the form of dogs, cats, and monkeys. The patient says that these symptoms have been present for more than 2 weeks. Past medical history is significant for simple partial seizures for which he takes valproate, but he has not had his medication adjusted in several years. His vital signs include: blood pressure of 124/76 mm Hg, heart rate of 98/min, respiratory rate of 12/min, and temperature of 37.1°C (98.8°F). On physical examination, the patient is alert and oriented to person, time, and place. Affect is not constricted or flat. Speech is of rapid rate and high volume. Pupils are equal and reactive bilaterally. The results of a urine drug screen are as follows:
Alcohol positive
Amphetamine negative
Benzodiazepine negative
Cocaine positive
GHB negative
Ketamine negative
LSD negative
Marijuana negative
Opioids negative
PCP negative
Which of the following is the most likely diagnosis in this patient?

Accepted Answer

Illusion

Answer

Delusion

Answer

Alcohol withdrawal

Answer

Visual hallucination

Answer

Cocaine intoxication

Question 7

A 24-year-old woman is brought to the hospital by her mother because she has "not been herself" for the past 3 months. The patient says she hears voices in her head. The mother said that when she is talking to her daughter she can’t seem to make out what she is saying; it is as if her thoughts are disorganized. When talking with the patient, you notice a lack of energy and an apathetic affect. Which of the following is the most likely diagnosis for this patient?

Accepted Answer

Schizophreniform disorder

Answer

Major depressive disorder

Answer

Schizophrenia

Answer

Brief psychotic disorder

Answer

Schizotypal disorder

Question 8

A 20-year-old man comes to the physician because of decreasing academic performance at his college for the past 6 months. He reports a persistent fear of “catching germs” from his fellow students and of contracting a deadly disease. He finds it increasingly difficult to attend classes. He avoids handshakes and close contact with other people. He states that when he tries to think of something else, the fears “keep returning” and that he has to wash himself for at least an hour when he returns home after going outside. Afterwards he cleans the shower and has to apply disinfectant to his body and to the bathroom. He does not drink alcohol. He used to smoke cannabis but stopped one year ago. His vital signs are within normal limits. He appears anxious. On mental status examination, he is oriented to person, place, and time. In addition to starting an SSRI, which of the following is the most appropriate next step in management?

Accepted Answer

Cognitive-behavioral therapy

Answer

Psychodynamic psychotherapy

Answer

Motivational interviewing

Answer

Interpersonal therapy

Answer

Group therapy

Question 9

A 79-year-old woman who lives alone is brought to the emergency department by her neighbor because of worsening confusion over the last 2 days. Due to her level of confusion, she is unable to answer questions appropriately. She has had type 2 diabetes mellitus for 29 years for which she takes metformin. Vital signs include: blood pressure 111/72 mm Hg, temperature 38.5°C (101.3°F), and pulse 100/min. Her fingerstick blood glucose is 210 mg/dL. On physical examination, she is not oriented to time or place and mistakes the nursing assistant for her cousin. Laboratory results are shown:
Hemoglobin 13 g/dL
Leukocyte count 16,000/mm3
Segmented neutrophils 70%
Eosinophils 1%
Basophils 0.3%
Lymphocytes 25%
Monocytes 4%
Which of the following is the most likely diagnosis?

Accepted Answer

Delirium

Answer

Brief psychotic disorder

Answer

Alzheimer's dementia

Answer

Depression

Answer

Delusional disorder

Question 10

A 16-year-old boy is brought in to a psychiatrist's office by his mother for increasingly concerning erratic behavior. Her son has recently entered a new relationship, and he constantly voices beliefs that his girlfriend is cheating on him. He ended his last relationship after voicing the same beliefs about his last partner. During the visit, the patient reports that these beliefs are justified, since everyone at school is “out to get him.” He says that even his teachers are against him, based on their criticism of his schoolwork. His mother adds that her son has always held grudges against people and has always taken comments very personally. The patient has no psychiatric history and is in otherwise good health. What condition is this patient genetically predisposed for?

Accepted Answer

Schizophrenia

Answer

Antisocial personality disorder

Answer

Major depressive disorder

Answer

Narcolepsy

Answer

Substance use disorder

Delusional disorder

Study Resources

Lessons

Questions

Flashcards

Lessons

Diagnostic criteria for delusional disorder

Types of delusional disorder (persecutory, jealous, etc.)

Differentiation from schizophrenia

Shared psychotic disorder (folie à deux)

Neurobiological basis of delusions

Cognitive theories of delusion formation

Cultural aspects of delusional beliefs

Assessment techniques for delusions

Pharmacological management

Psychotherapeutic approaches

Course and prognosis

Legal and ethical considerations

Delusional disorder in special populations

Practice Questions

Flashcards

About Delusional disorder for USMLE

Lessons in Delusional disorder

Master Delusional disorder