Endocrine Pathology Practice Questions

Question 1

TRH stimulation testing is useful in diagnosis of disorders of the following hormones?

Accepted Answer

Growth hormone

Answer

PTH

Answer

ACTH

Answer

Insulin

Question 2

What is the primary function of the paraventricular and supraoptic nuclei?

Accepted Answer

Regulate water balance.

Answer

All of the options.

Answer

Destruction can lead to diabetes insipidus.

Answer

Are located in the anterior pituitary.

Question 3

A patient presents with palpitations, headache, and sweating. His BP is $180/100 \mathrm{mmHg}$ . 24-hour urinary metanephrine values are elevated. What is the diagnosis?

Accepted Answer

Pheochromocytoma

Answer

Carcinoid crisis

Answer

Neuroblastoma

Answer

Carcinoid tumor

Question 4

Which of the following mechanisms is NOT responsible for complications in Diabetes Mellitus?

Accepted Answer

Chronic inflammation

Answer

Non-enzymatic glycosylation

Answer

Protein Kinase C activation

Answer

Disturbance in polyol pathway

Question 5

Pheochromocytoma are tumors of which structure?

Accepted Answer

Adrenal medulla

Answer

Adrenal cortex

Answer

Pancreas

Answer

Bone

Question 6

Expression of which of the following oncogenes is associated with a high incidence of medullary carcinoma of the thyroid?

Accepted Answer

RET Proto oncogene

Answer

FOS

Answer

BRAF

Answer

WNT1

Question 7

A biopsy from the parathyroid gland of a 55-year-old male, a known case of chronic kidney disease with hypertension and type II diabetes who recently developed bone pain, skin lesions, and recurrent kidney stones, is shown below. What is the most likely histopathological finding?

Accepted Answer

Water clear cells in parathyroid hyperplasia

Answer

Water clear cells in parathyroid carcinoma

Answer

Tuberculous parathyroiditis

Answer

Parathyroid necrosis

Question 8

The neuroendocrine carcinoma arising from parafollicular 'C' cells of thyroid is:

Accepted Answer

Medullary carcinoma

Answer

Papillary carcinoma

Answer

Follicular carcinoma

Answer

Anaplastic carcinoma

Question 9

A 30-year-old woman presents with headache, visual disturbances, deepening of the voice, generalized weakness, amenorrhea for one year, and a recent requirement for a larger shoe size. Laboratory studies show impaired glucose tolerance. What additional diagnostic procedure would be most useful?

Accepted Answer

Magnetic resonance imaging of the sella turcica

Answer

Complete blood count with differential count

Answer

Computed tomography scan of the abdomen

Answer

Test for serum 21-hydroxylase activity

Question 10

A 50-year-old man with fasting blood glucose >140 mg/dL on two occasions is put on a restricted caloric diet and started on a glucagon-like peptide-1 (GLP-1) receptor agonist. Which of the following laboratory studies is most likely to afford the best method of monitoring disease control in this man?

Accepted Answer

Glycosylated hemoglobin

Answer

Cholesterol, total

Answer

Fasting plasma glucose

Answer

Microalbuminuria

Endocrine Pathology

Study Resources

Lessons

Questions

Flashcards

Lessons

Pituitary Gland Disorders

Thyroid Gland Diseases

Parathyroid Gland Pathology

Adrenal Cortical Disorders

Adrenal Medullary Disorders

Pancreatic Endocrine Disorders

Multiple Endocrine Neoplasia Syndromes

Diffuse Neuroendocrine System

Pineal Gland Pathology

Laboratory Diagnosis of Endocrine Diseases

Practice Questions

Flashcards

About Endocrine Pathology for NEET-PG

Lessons in Endocrine Pathology

Master Endocrine Pathology