Cosmetic Dermatology Indian Medical PG Practice Questions and MCQs
Practice Indian Medical PG questions for Cosmetic Dermatology. These multiple choice questions (MCQs) cover important concepts and help you prepare for your exams.
Cosmetic Dermatology Indian Medical PG Question 1: Dermatitis may be a clinical manifestation of deficiency states of all of the following nutrients except -
- A. Biotin
- B. Niacin
- C. Pyridoxine
- D. Thiamine (Correct Answer)
Cosmetic Dermatology Explanation: ***Thiamine***
- A deficiency in **thiamine (vitamin B1)** primarily affects the nervous and cardiovascular systems, leading to conditions like **beriberi**, characterized by neuropathy, heart failure, and Wernicke-Korsakoff syndrome.
- Dermatitis is **not a typical or direct clinical manifestation** of thiamine deficiency.
*Biotin*
- **Biotin (vitamin B7)** deficiency can cause **dermatitis**, often described as a scaly, erythematous rash around the eyes, nose, and mouth.
- Hair loss (**alopecia**) and **neurological symptoms** are also associated with biotin deficiency.
*Niacin*
- **Niacin (vitamin B3)** deficiency leads to **pellagra**, classically presenting with the "3 Ds": **dermatitis**, **diarrhea**, and **dementia**.
- The dermatitis in pellagra is typically symmetrical and photosensitive, affecting sun-exposed areas.
*Pyridoxine*
- **Pyridoxine (vitamin B6)** deficiency can result in **seborrheic dermatitis-like rash**, especially around the eyes, nose, and mouth.
- Other symptoms include **glossitis**, **cheilosis**, and **neurological disturbances** like peripheral neuropathy.
Cosmetic Dermatology Indian Medical PG Question 2: Chemical peeling is indicated in all of the following except
- A. Melasma
- B. Acne vulgaris
- C. Photoaging
- D. Lichen planus (Correct Answer)
Cosmetic Dermatology Explanation: ***Lichen planus***
- Chemical peels are generally **contraindicated** in active inflammatory conditions like **lichen planus**, as they can worsen the inflammation or trigger a Koebner phenomenon.
- While chemical peels can address post-inflammatory hyperpigmentation, they should not be used during the active phase of lichen planus due to the risk of exacerbation.
*Melasma*
- **Melasma** is a common indication for chemical peels, particularly superficial and medium-depth peels, to reduce hyperpigmentation.
- Peels containing agents like **glycolic acid**, salicylic acid, or trichloroacetic acid are often used to lighten melanin deposits.
*Acne vulgaris*
- Chemical peels are effective in treating **acne vulgaris** by exfoliating the skin, reducing comedones, and improving overall skin texture.
- **Salicylic acid peels** are particularly useful due to their lipophilic nature, allowing them to penetrate and clean pores.
*Photoaging*
- **Photoaging**, characterized by fine lines, wrinkles, and dyspigmentation from sun exposure, is a primary indication for chemical peels.
- Peels can promote **collagen remodeling** and help achieve a more even skin tone and smoother texture.
Cosmetic Dermatology Indian Medical PG Question 3: Match List-I with List-II and select the correct answer using the code given below the Lists:
(Refer to the image for List-I and List-II)
- A. A→2 B→3 C→4 D→1
- B. A→3 B→4 C→1 D→2
- C. A→4 B→1 C→2 D→3 (Correct Answer)
- D. A→1 B→2 C→3 D→4
Cosmetic Dermatology Explanation: ***A→4, B→1, C→2, D→3***
**Correct Matching:**
**Tattooing (A) → Foreign particles like dirt, soot (4)**
- Tattooing refers to permanent skin discoloration caused by **foreign pigment insertion** into the dermis
- Commonly occurs accidentally after trauma with **dirt, soot, gunpowder, or other foreign particles**
- The particles become embedded in the skin causing permanent discoloration
**Keloid (B) → Outgrows boundaries of original wound (1)**
- A keloid is a **prominent raised scar** that extends beyond the margins of the original injury
- Results from excessive collagen deposition during abnormal wound healing
- **Key feature**: Growth exceeds the boundaries of the original wound area
**Dupuytren's contracture (C) → Contractures (2)**
- Progressive fibrosis of the **palmar fascia** leading to finger contractures
- Causes permanent flexion deformity, typically affecting the ring and little fingers
- Results in functional limitation due to **contracture formation**
**Basal cell carcinoma (D) → Not familial (3)**
- Most common skin malignancy, typically **sporadic** rather than familial
- Associated with UV exposure, fair skin, and immunosuppression
- Unlike some other cancers, **typically not inherited** in familial patterns
*Incorrect Options:*
*A→2, B→3, C→4, D→1*
- Incorrectly matches tattooing with contractures and Dupuytren's with foreign particles
*A→3, B→4, C→1, D→2*
- Incorrectly matches tattooing with non-familial trait and keloid with foreign particles
*A→1, B→2, C→3, D→4*
- Incorrectly matches tattooing with outgrowing boundaries and basal cell carcinoma with foreign particles
Cosmetic Dermatology Indian Medical PG Question 4: PUVA therapy is used in all except:
- A. Psoriasis
- B. Vitiligo
- C. Mycosis fungoides
- D. Melasma (Correct Answer)
Cosmetic Dermatology Explanation: ***Melasma***
- **PUVA (Psoralen plus UVA) therapy** is contraindicated in melasma due to its potential to worsen hyperpigmentation and cause paradoxical darkening.
- Melasma is best managed with topical agents like **hydroquinone**, **tretinoin**, and chemical peels, along with strict **sun protection**.
*Psoriasis*
- **PUVA therapy** is a well-established and effective treatment for moderate to severe psoriasis, especially for patients with widespread plaques.
- It works by inhibiting DNA synthesis and cell proliferation in rapidly dividing keratinocytes, leading to a reduction in psoriatic lesions.
*Vitiligo*
- **PUVA therapy** is a common treatment for vitiligo, stimulating melanocyte activity and promoting repigmentation in affected areas.
- Psoralen sensitizes melanocytes to UVA light, which then encourages melanin production.
*Mycosis fungoides*
- In its early stages, **mycosis fungoides**, a cutaneous T-cell lymphoma, can be effectively treated with **PUVA therapy**.
- PUVA induces apoptosis of malignant T-cells in the skin, leading to remission of skin lesions.
Cosmetic Dermatology Indian Medical PG Question 5: Which of the following is an example of topical administration producing only local effects (not systemic)?
- A. Topical corticosteroid cream (Correct Answer)
- B. Sublingual nitroglycerin
- C. Transdermal patch
- D. Rectal diazepam
Cosmetic Dermatology Explanation: ***Topical corticosteroid cream***
- When applied to the skin for conditions like dermatitis, topical corticosteroids primarily exert their effects at the site of application, reducing **local inflammation** and itching.
- While systemic absorption can occur with potent steroids over large areas, typical use aims for **localized action** without significant systemic effects.
*Sublingual nitroglycerin*
- This route is designed for **rapid systemic absorption** through the oral mucosa, bypassing first-pass metabolism to quickly treat angina.
- The goal is a **widespread vasodilatory effect** throughout the body, not a local one within the mouth.
*Transdermal patch*
- Transdermal patches, such as those for nicotine or fentanyl, are specifically designed to deliver medication **systemically** through the skin into the bloodstream over a prolonged period.
- They provide a **sustained release** and systemic therapeutic effect throughout the body.
*Rectal diazepam*
- Administered rectally, diazepam is absorbed into the systemic circulation to produce **CNS effects** such as sedation, anxiolysis, or anticonvulsant activity.
- Although the administration is local, the intended clinical effect is **systemic** and widespread throughout the body.
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