Antiparasitic medications

A 29-year-old man from India seeks evaluation at a clinic with complaints of sore muscles and lethargy of several days duration. After the physical examination and laboratory testing, the patient is asked to stay for treatment and monitoring. Despite the physician’s warning, the patient leaves the hospital against medical advice. He subsequently develops difficulty in breathing and anuria and is brought to the emergency department with loss of consciousness. The patient gets an immediate T2 weighted image of his head, which is shown in the exhibit. Laboratory findings confirm the presence of rings, which appear on the periphery of red blood cells (RBCs). What is the best treatment for his condition?

A 7-year-old girl is brought to the physician by her mother because of a 4-week history of irritability, diarrhea, and a 2.2-kg (5-lb) weight loss that was preceded by a dry cough. The family returned from a vacation to Indonesia 2 months ago. Her vital signs are within normal limits. Abdominal examination shows mild tenderness with no guarding or rebound and increased bowel sounds. Her leukocyte count is 9,200/mm3 with 20% eosinophils. A photomicrograph of a wet stool mount is shown. Which of the following is the most appropriate pharmacotherapy?