Multifactorial Inheritance Disorders — MCQs

Which of the following disorders is most commonly associated with multifactorial inheritance?

The risk of recurrence of congenital heart disease for subsequent pregnancies in families with one affected child is:

The commonest mode of inheritance of congenital heart disease is

Risk of genetic diseases in consanguineous marriage between first cousins?

Which one of the following is an autosomal dominant disorder?

A 25-year-old man presents for a routine physical examination. The patient is tall (6 ft. 5 in) and on examination he was found to have an early diastolic murmur. His family pedigree is as given below. Which of the following is the mode of inheritance by which the disease is likely to be transmitted?

A researcher wants to determine whether there is an association between CRP values and the risk of MI or cancer. Four relative risk (RR) values were plotted $(0.5,1.5,1.7,1.8)$ with respect to CRP levels. What conclusion can be drawn?

What is the chance of a child having cystic fibrosis if both parents are carriers of the disease?

Neonate is brought at 3 weeks of age, with projectile vomiting. USG was performed and is shown below. When can the abdominal mass in this condition be best palpated?

An infant brought to the clinic with non-bilious projectile vomiting. The investigation of choice includes: