Question 1

Question

A 58-year-old man with a 40-pack-year smoking history presents with progressive dyspnea and a dry cough. Chest CT reveals bilateral pleural plaques and a right pleural mass. A pleural lesion biopsy is performed. The photomicrograph shows elongated, beaded golden-brown structures within macrophages, surrounded by a fibrous stroma with atypical mesothelial cells forming tubular and papillary patterns. Which of the following best describes the structures characteristic of asbestos exposure identified in this biopsy?

Accepted Answer

Ferruginous bodies formed by iron-protein coating over inhaled mineral fibers

Answer

Psammoma bodies representing dystrophic calcification within laminated concentric rings

Answer

Schaumann bodies representing calcified protein aggregates within giant cells

Answer

Asteroid bodies representing crystalline lipid inclusions within multinucleated giant cells

Answer

Charcot-Leyden crystals derived from eosinophil granule membrane proteins

Systemic Pathology — MCQs

Systemic Pathology — MCQs

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