Pancreatitis — MCQs

A 50-year-old woman comes to the physician because of multiple, ulcerative skin lesions that occur over various parts of her body. She reports that these rashes first appeared 6 months ago. They occur episodically and usually start as reddish spots, which then expand in size and ulcerate over the next ten days. They resolve spontaneously and reappear at another location a few days later. Over the past 6 months, she has had multiple episodes of diarrhea. She has lost 8 kg weight over this period and feels tired constantly. She has not had fever. She was treated for deep venous thrombosis 3 years ago, and took medication for it for 6 months after the episode. Her vital signs are within normal limits. She appears pale and has multiple, tender, ulcerative skin lesions on her legs and buttocks. Her hemoglobin is 9.6 mg/dL, mean corpuscular volume is 82 μm3, and fingerstick blood glucose concentration is 154 mg/dL. Her serum glucagon is elevated. Abdominal ultrasonography reveals a 5.6 cm, well-demarcated, hypoechoic mass in the pancreatic body and multiple, small masses in the liver of variable echogenicity. Which of the following is the most appropriate next step in management of this patient?

A 61-year-old diabetic woman is brought to the emergency department with the complaint of multiple bouts of abdominal pain in the last 24 hours. She says that the pain is dull aching in nature, radiates to the back, and worsens with meals. She also complains of nausea and occasional vomiting. She has been hospitalized repeatedly in the past with similar complaints. Her temperature is 37° C (98.6° F), respiratory rate is 16/min, pulse is 77/min, and blood pressure is 120/89 mm Hg. On physical exam, dark hyperpigmentation of the axillary skin is noted. Her blood test report from last month is given below: Glycated hemoglobin (HbA1c): 9.1% Triglyceride: 675 mg/dL LDL-Cholesterol: 102 mg/dL HDL-Cholesterol: 35 mg/dL Total Cholesterol: 250 mg/dL Serum Creatinine: 1.2 mg/dL BUN: 12 mg/dL Alkaline phosphatase: 100 U/L Alanine aminotransferase: 36 U/L Aspartate aminotransferase: 28 U/L What is the most likely diagnosis in this case?