Transplantation in Special Populations Practice Questions

Question 1

HLA typing is useful in:

Accepted Answer

Organ transplant

Answer

Disputed paternity

Answer

Dactylography

Answer

Thanatology

Question 2

Which of the following is true regarding extended criteria donors for liver transplantation?

Accepted Answer

Donors aged >60 years with no significant comorbidities

Answer

Donors with well-controlled diabetes mellitus

Answer

Hepatitis C antibody positive donors

Answer

Donors with significant uncontrolled comorbidities

Question 3

Which of the following is not true about lupus nephritis in pregnancy?

Accepted Answer

Ecosprin, methotrexate, cyclophosphamide, corticosteroids, azathioprine are safe in pregnancy

Answer

Pregnancy to be planned once the disease has been quiescent for at least 6 months and there is no evidence of renal dysfunction

Answer

High dose corticosteroids for lupus flare in pregnancy is safe

Answer

Immunosuppression can be continued during pregnancy

Question 4

What is the most common viral illness transmitted via homologous blood transfusion?

Accepted Answer

Hepatitis B (HBV)

Answer

Hepatitis C (HCV)

Answer

HIV

Answer

Cytomegalovirus (CMV)

Question 5

Most common infection post solid organ transplantation

Accepted Answer

CMV

Answer

EBV

Answer

HSV

Answer

HPV

Question 6

What is the most common type of graft rejection?

Accepted Answer

Acute

Answer

Hyperacute

Answer

Chronic

Answer

Acute on chronic

Question 7

After the first postoperative year of cardiac transplantation, what is the most common cause of death?

Accepted Answer

Accelerated graft arteriosclerosis

Answer

Infection

Answer

Arrhythmia

Answer

Acute rejection episode

Question 8

Infection in a renal transplant patient is usually caused by which pathogen?

Accepted Answer

Cytomegalovirus (CMV)

Answer

Human Immunodeficiency Virus (HIV)

Answer

Herpes Simplex Virus (HSV)

Answer

Salmonella

Question 9

What type of graft is a graft from a sister to a brother?

Accepted Answer

Allograft

Answer

Isograft

Answer

Autograft

Answer

Heterograft

Question 10

Compared to early immunosuppressive drugs such as azathioprine, steroids, and anti-lymphocyte serum, what specific advantages do newer immunosuppressive agents offer?

Accepted Answer

Tacrolimus (FK506) shares properties with cyclosporine but is particularly useful for rescuing grafts failing under cyclosporine therapy.

Answer

Cyclosporine interferes with lymphokine production and has neither bone marrow nor renal toxicity.

Answer

Monoclonal antibody (OKT3) is more available, more specific, and has fewer side effects than anti-lymphocyte serum.

Answer

None of the above.

Transplantation in Special Populations — MCQs

Transplantation in Special Populations — MCQs

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