Wound Care and Dressings — MCQs
The image shows a Negative Pressure Wound Therapy (NPWT) dressing applied to a patient's wound. What is the ideal negative pressure range commonly used for NPWT to promote wound healing?
A patient with grossly contaminated wound presents 12 hours after an accident. His wound should be managed by -
A child presented with bloody stools and abdominal pain. Which enrichment medium should be used for processing the fecal sample?
Maximum collagen deposition in wound healing is seen at -
Which of the following statements about burns is NOT true?
Which of the following statements about wound healing is false?
Closure for clean wounds within 6 hours of injury is called.
Which of the following factors is NOT used to differentiate between antemortem and postmortem wounds?
Which of the following actions is NOT recommended when dealing with a patient who has been bitten by a snake?
What is the most common cause of postoperative fever on the first postoperative day?
Wound Care and Dressings Indian Medical PG Practice Questions and MCQs
Question 1: The image shows a Negative Pressure Wound Therapy (NPWT) dressing applied to a patient's wound. What is the ideal negative pressure range commonly used for NPWT to promote wound healing?
- A. -125 mm Hg (Correct Answer)
- B. 60-80 mm Hg
- C. 130 mm Hg
- D. 80-100 mm Hg
Explanation: ***-125 mm Hg*** - **Negative Pressure Wound Therapy (NPWT)** uses controlled subatmospheric (negative) pressure to promote wound healing. - The most commonly used pressure setting is **-125 mm Hg**, which has been extensively validated in clinical studies. - This pressure level effectively promotes granulation tissue formation, reduces edema, removes exudate, and increases blood flow to the wound bed. - **-75 to -125 mm Hg** is the typical therapeutic range, with -125 mm Hg being the standard setting for most wound types. *60-80 mm Hg* - This represents **positive pressure**, not negative pressure used in NPWT. - NPWT requires subatmospheric (below atmospheric) pressure, denoted by the negative sign. - Positive pressures in this range would be used in compression therapy for venous insufficiency, not vacuum-assisted wound closure. *130 mm Hg* - This is a **positive pressure** value and does not apply to NPWT. - NPWT uses negative (suction) pressure, not positive compression. - If interpreted as -130 mm Hg, this would be at the higher end and might increase patient discomfort without additional benefit over -125 mm Hg. *80-100 mm Hg* - These are **positive pressure** values not used in NPWT. - NPWT specifically requires negative pressure (vacuum/suction) to work effectively. - This range would be excessively high even for compression therapy and inappropriate for NPWT.
Question 2: A patient with grossly contaminated wound presents 12 hours after an accident. His wound should be managed by -
- A. Thorough cleaning with debridement of all dead and devitalised tissue without primary closure (Correct Answer)
- B. Primary closure over a drain
- C. Covering the defect with split skin graft after cleaning
- D. Thorough cleaning and primary repair
Explanation: ***Thorough cleaning with debridement of all dead and devitalised tissue without primary closure*** - For a **grossly contaminated wound** presenting 12 hours after injury, thorough **wound lavage** and **debridement** of all non-viable tissue are crucial to reduce bacterial load. - **Delayed primary closure** or **secondary intention healing** is preferred over primary closure in such cases to prevent infection spread. *Primary closure over a drain* - **Primary closure** of a grossly contaminated wound significantly increases the risk of **wound infection**, even with a drain. - Drains may help with fluid collection but do not sufficiently mitigate the risk of infection in a dirty wound. *Covering the defect with split skin graft after cleaning* - Applying a **skin graft** to a potentially infected wound is contraindicated as it will likely fail due to the **bacterial burden**. - Grafting is typically performed on clean, well-vascularized wound beds. *Thorough cleaning and primary repair* - While **thorough cleaning** is essential, **primary repair** (closure) of a grossly contaminated wound is associated with a high risk of **surgical site infection**. - **Delayed closure** allows for observation and further debridement if necessary.
Question 3: A child presented with bloody stools and abdominal pain. Which enrichment medium should be used for processing the fecal sample?
- A. Blood agar
- B. Selenite F broth (Correct Answer)
- C. Alkaline peptone water
- D. Muller Hinton Broth
Explanation: ***Selenite F broth*** - This **enrichment medium** is specifically designed to isolate **Salmonella** and some species of **Shigella**, which are common causes of bloody stools and abdominal pain in children. - It inhibits the growth of commensal gut flora, allowing pathogenic bacteria to proliferate and be subsequently identified on selective media. *Blood agar* - Blood agar is a **general-purpose enrichment medium** that supports the growth of a wide range of bacteria but does not selectively enrich for specific pathogens. - It would be ineffective in outcompeting the normal fecal flora to isolate rarer enteric pathogens causing the symptoms. *Alkaline peptone water* - This medium is primarily used for the enrichment of **Vibrio cholerae** species, which typically cause watery diarrhea, not bloody stools. - While it helps in the isolation of *Vibrio* species, it is not suitable for the suspected pathogens in this clinical scenario. *Muller Hinton Broth* - Muller-Hinton media are primarily used for **antimicrobial susceptibility testing** (antibiotic sensitivity testing) and are not designed for the primary isolation or enrichment of specific pathogens from clinical samples. - It would not provide a selective advantage for the recovery of organisms causing bloody diarrhea from a fecal sample.
Question 4: Maximum collagen deposition in wound healing is seen at -
- A. End of third week (Correct Answer)
- B. End of first week
- C. End of 2 months
- D. End of second week
Explanation: ***End of third week*** - By the end of the **third week**, the proliferative phase of wound healing is well underway, characterized by significant **collagen deposition**. [1] - At this stage, **Type III collagen** is initially laid down, which is later replaced by stronger **Type I collagen**, contributing to increasing wound strength. *End of first week* - The first week primarily involves the **inflammatory phase** and the initial stages of **proliferation**, with minimal new collagen deposition. [2] - While some **fibroblasts** are present, the amount of collagen synthesized is still relatively low. *End of second week* - Collagen synthesis is ongoing during the second week, but the **peak deposition rate** and overall amount of collagen accumulated are typically not as high as at the end of the third week. - The wound is gaining strength, but further increase in collagen content and remodeling is yet to occur. *End of 2 months* - By 2 months, the wound is in the **remodeling phase**, where the total collagen content might be substantial but the *rate of new collagen synthesis* has slowed down. - At this stage, there is a balance between **collagen synthesis** and **degradation**, and the collagen fibers are being reorganized and cross-linked to further improve tensile strength. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Inflammation and Repair, pp. 117-119. [2] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Inflammation and Repair, p. 115.
Question 5: Which of the following statements about burns is NOT true?
- A. Pseudomonas is a common infection in burn wounds.
- B. Cephalosporins are not the drug of choice for burn management.
- C. Moist dressings are beneficial for burn care. (Correct Answer)
- D. Toxic shock syndrome is uncommon in burn patients.
Explanation: ***Moist dressings are beneficial for burn care.*** - This statement is **NOT true** in the traditional sense being implied here. - While **modern wound care** does favor maintaining a moist wound environment for many wound types, **burn management** specifically uses **topical antimicrobial agents** (like silver sulfadiazine, mafenide acetate) rather than simple "moist dressings." - Traditional moist dressings without antimicrobial properties can actually **increase infection risk** in burns. - The key principle is **antimicrobial coverage**, not just maintaining moisture. *Pseudomonas is a common infection in burn wounds.* - **Pseudomonas aeruginosa** is indeed one of the most common and serious pathogens in burn wounds. - It thrives in the moist, protein-rich environment of burn injuries and is notoriously difficult to treat due to antibiotic resistance. - Pseudomonas infection significantly increases morbidity and mortality in burn patients. *Cephalosporins are not the drug of choice for burn management.* - This statement is **TRUE**. - **Topical antimicrobials** (silver sulfadiazine, mafenide acetate, silver-impregnated dressings) are the primary agents for burn wound management. - Systemic antibiotics, including cephalosporins, are **not used prophylactically** and are reserved for documented infections. - When systemic treatment is needed, it is **culture-guided**, and for Pseudomonas coverage, anti-pseudomonal agents are preferred. *Toxic shock syndrome is uncommon in burn patients.* - **Toxic Shock Syndrome (TSS)** from *Staphylococcus aureus* or *Streptococcus pyogenes* is indeed a **rare but serious complication** in burn patients. - While burns create a susceptible environment for bacterial colonization, TSS remains uncommon compared to other infectious complications.
Question 6: Which of the following statements about wound healing is false?
- A. Inhibited by diabetes mellitus (DM)
- B. Inhibited by foreign body
- C. Hematomas promote wound healing (Correct Answer)
- D. Inhibited by infection
Explanation: ***Hematomas promotes wound healing*** - Hematomas (localized collections of **blood outside blood vessels**) actually **inhibit wound healing** by acting as a medium for bacterial growth and increasing tissue tension. - This statement is **false** because hematomas interfere with proper tissue apposition and oxygen delivery, which are crucial for successful wound repair [3]. *Inhibited by diabetes mellitus (DM)* - **Diabetes mellitus** impairs various stages of wound healing due to **poor glycemic control**, leading to compromised immune function, neuropathy, and reduced blood flow [1]. - This often results in **delayed wound closure** and increased risk of infection [2]. *Inhibited by foreign body* - The presence of a **foreign body** in a wound can lead to a persistent inflammatory response, impeding tissue repair and increasing the likelihood of chronic infection. - This sustained inflammation prevents the orderly progression through the phases of wound healing, thus **inhibiting the process**. *Inhibited by infection* - **Infection** in a wound significantly delays healing by causing ongoing inflammation, tissue destruction, and increased metabolic demands [1]. - Bacteria compete for nutrients and produce toxins that harm host cells, preventing proper **granulation tissue formation** and **epithelialization**. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Inflammation and Repair, pp. 116-117. [2] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. (Basic Pathology) introduces the student to key general principles of pathology, both as a medical science and as a clinical activity with a vital role in patient care. Part 2 (Disease Mechanisms) provides fundamental knowledge about the cellular and molecular processes involved in diseases, providing the rationale for their treatment. Part 3 (Systematic Pathology) deals in detail with specific diseases, with emphasis on the clinically important aspects., pp. 110-111. [3] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. (Basic Pathology) introduces the student to key general principles of pathology, both as a medical science and as a clinical activity with a vital role in patient care. Part 2 (Disease Mechanisms) provides fundamental knowledge about the cellular and molecular processes involved in diseases, providing the rationale for their treatment. Part 3 (Systematic Pathology) deals in detail with specific diseases, with emphasis on the clinically important aspects., pp. 106-107.
Question 7: Closure for clean wounds within 6 hours of injury is called.
- A. Primary closure (Correct Answer)
- B. Delayed primary closure
- C. Secondary closure
- D. Tertiary closure
Explanation: ***Primary closure*** - **Primary closure** is the immediate closure of a wound, typically within **6 hours** of injury, for **clean wounds** at low risk of infection. - This method promotes direct apposition of wound edges, leading to **faster healing** and **minimal scarring**. *Delayed primary closure* - This involves leaving a wound open for **4-6 days** to monitor for infection or edema, then closing it if conditions are favorable. - It is often used for **contaminated wounds** or those with a higher risk of infection, where immediate closure is not safe. - Also known as **tertiary closure**. *Secondary closure* - **Secondary closure**, or healing by secondary intention, occurs when a wound is left open and allowed to **heal naturally by granulation, contraction, and epithelialization**. - This method is used for **heavily contaminated** or **infected wounds** and results in a larger scar and a longer healing time. *Tertiary closure* - **Tertiary closure** is another term for **delayed primary closure**. - It involves leaving a wound open initially, then closing it after several days (typically 4-6 days) once the risk of infection has decreased. - This option is incorrect because the question asks about closure **within 6 hours**, not delayed closure.
Question 8: Which of the following factors is NOT used to differentiate between antemortem and postmortem wounds?
- A. Everted margins
- B. Depth of the wound (Correct Answer)
- C. Blood clots in surrounding
- D. Swollen edges
Explanation: ***Depth of the wound*** - The **depth of a wound** itself does not differentiate between antemortem (before death) and postmortem (after death) injuries, as both can vary in depth. - While deep wounds are more likely to be lethal, the depth doesn't indicate if the injury occurred when the person was alive or after death. *Everted margins* - **Everted margins** (edges that are turned outward) are typically associated with **antemortem wounds**, particularly incised or stab wounds, due to skin elasticity and tissue reactivity. - Postmortem wounds often show flat or inverted margins as there is no muscle tone or tissue response. *Blood clots in surrounding* - The presence of **organized blood clots** or **vital reactions** like inflammation and healing in the tissues surrounding a wound strongly indicates an **antemortem injury**, as these processes require an intact circulatory system. - In postmortem wounds, blood may simply pool without clotting or show signs of tissue reaction, or it may be absent altogether. *Swollen edges* - **Swollen edges** around a wound are a sign of **inflammation** and **tissue edema**, which are physiological responses to injury that can only occur in a living individual. - This vital reaction points to an **antemortem injury**, as a body post-mortem lacks the metabolic processes necessary for such swelling.
Question 9: Which of the following actions is NOT recommended when dealing with a patient who has been bitten by a snake?
- A. Reassurance
- B. Immobilization of the affected limb
- C. Clean with soap and water
- D. Local incision (Correct Answer)
Explanation: ***Local incision*** - Making an incision at the bite site can **worsen tissue damage**, increase the risk of infection, and does not effectively remove venom. - This practice is **outdated** and potentially harmful, as venom spreads rapidly through the lymphatic system rather than being localized in a way that incision can help. - **Local incision is NOT recommended** and is a contraindicated first-aid measure. *Immobilization of the affected limb* - Immobilizing the bitten limb helps **slow the spread of venom** through the lymphatic system. - This is a **recommended first-aid measure**, especially for neurotoxic snakebites, and should be done by keeping the limb at or below heart level. - Proper immobilization involves splinting the limb without restricting blood flow. *Reassurance* - Overt fear and anxiety can lead to symptoms like **tachycardia** and **hypertension**, which can exacerbate the effects of the venom. - **Calming the patient** helps reduce the physiological stress response, which is crucial as panic can worsen the clinical picture. - Reassurance is a **recommended supportive measure**. *Clean with soap and water* - Cleaning the wound helps remove surface venom and **reduce the risk of secondary bacterial infection**. - This is a **recommended basic first-aid measure** that promotes wound hygiene without interfering with venom management.
Question 10: What is the most common cause of postoperative fever on the first postoperative day?
- A. Atelectasis (Correct Answer)
- B. Wound infection
- C. Pulmonary embolism
- D. UTI
Explanation: ***Atelectasis*** - **Atelectasis** is the most common cause of fever on the **first postoperative day** due to the collapse of lung alveoli, leading to impaired gas exchange. - It is frequently caused by **anesthesia, pain, and immobility** reducing deep breaths and coughing. *Wound infection* - **Wound infections** typically manifest later, generally around **3 to 7 days post-surgery**, as bacterial growth and inflammation require more time. - While it can cause fever, it is unlikely to be the cause within the **first 24-48 hours**. *Pulmonary embolism* - A **pulmonary embolism** is a serious complication, but fever is not its primary or most common early symptom; instead, patients often present with **dyspnea, tachypnea, and chest pain.** - Although it can occur, it's generally less frequent on the **first postoperative day** compared to atelectasis. *UTI* - **Urinary tract infections (UTIs)** usually develop a few days after surgery, often associated with **catheterization**, and present with dysuria, frequency, and suprapubic pain. - While fever can occur with a UTI, it is rarely the cause of fever within the **first 24 hours** after surgery.
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