Drug Interactions — MCQs

Pharmacodynamics deals with:-

An SSRI antidepressant, such as fluoxetine, will be prescribed for an adult patient. You should advise him or her that two of the most likely side effects or adverse responses that may eventually occur at therapeutic blood levels are which of the following?

What is the mechanism of metabolism for alcohol, aspirin, and phenytoin at high doses?

All are true for cytochrome P450 enzymes EXCEPT:

A patient on SSRI sertraline was also prescribed amitriptyline and subsequently developed serotonin toxicity. What is the likely treatment for serotonin toxicity?

A 68-year-old with depression and chronic pain is on amitriptyline. What side effect may arise if given oxybutynin for overactive bladder?

A 25-year-old uncooperative patient of schizophrenia was brought in to the casualty. The Casualty Medical Officer gave an injectable drug to the patient. Two hours later patient develops the following posturing. What is the best treatment?

Clozapine is used in:

Which antipsychotic has anti-suicidal properties?

Use of lithium in pregnancy can result in which of the following abnormalities in the baby?