NEET-PG 2021 Practice Questions

Q: A patient presents with breathlessness and wheezing. Absolute eosinophil count is 500 cells/ $\mu \mathrm{L}$. Chest X-ray shows a miliary pattern. What is the most likely diagnosis?

Tropical pulmonary eosinophilia. ***Tropical pulmonary eosinophilia*** - This condition is characterized by **eosinophilia** (absolute eosinophil count >500 cells/µL), **respiratory symptoms** such as breathlessness and wheezing, and a **miliary pattern** on chest X-ray, all consistent with the patient's presentation. - It results from a **hypersensitivity reaction** to microfilariae from Wuchereria bancrofti or Brugia malayi in individuals living in endemic regions. *Bronchial asthma* - While bronchial asthma can cause **breathlessness** and **wheezing**, a miliary pattern on chest X-ray is **not typical**, nor is an eosinophil count of 500 cells/µL, though eosinophilia can occur. - Asthma is primarily a disease of reversible airway obstruction, often triggered by **allergens** or irritants. *Miliary Tuberculosis (TB)* - **Miliary TB** would present with a miliary pattern on chest X-ray and breathlessness, but it is typically associated with **low or normal eosinophil counts**, and wheezing is less common. - Fever, night sweats, and weight loss are also common symptoms of Miliary TB. *Hypersensitivity pneumonitis* - This condition involves inflammation of the lung alveoli due to inhalation of organic dusts or chemicals, causing **breathlessness** and, occasionally, wheezing, but **eosinophilia is not a primary feature**. - Chest X-ray findings can be diverse, but a **miliary pattern** is less specific than for tropical pulmonary eosinophilia. *Allergic bronchopulmonary aspergillosis (ABPA)* - ABPA can present with **eosinophilia**, **wheezing**, and respiratory symptoms, but chest X-ray typically shows **central bronchiectasis** and **fleeting infiltrates** rather than a miliary pattern. - It occurs in patients with asthma or cystic fibrosis and is characterized by **hypersensitivity to Aspergillus fumigatus**.

Q: A patient presents with breathing difficulty and generalized weakness. On auscultation, a middiastolic murmur with a prominent "a" wave is observed. What is the most likely diagnosis?

Tricuspid Stenosis (TS). ***Tricuspid Stenosis (TS)*** - A **middiastolic murmur** in the tricuspid area (usually left lower sternal border) along with a **prominent "a" wave** (due to increased right atrial pressure against a stenotic tricuspid valve) is pathognomonic for tricuspid stenosis. - The symptoms of **breathing difficulty** and **generalized weakness** can arise from reduced cardiac output and venous congestion characteristic of TS. *Mitral Regurgitation (MR)* - MR typically presents with a **holosystolic murmur** best heard at the apex and radiating to the axilla. - It does not characteristically produce a middiastolic murmur or a prominent "a" wave. *Mitral Stenosis (MS)* - MS causes a **diastolic rumble** with an **opening snap**, best heard at the apex, but it is not typically associated with a pronounced "a" wave in the jugular venous pulse unless there's associated pulmonary hypertension and right heart strain. - The murmur is usually localized to the apex, whereas tricuspid murmurs are typically heard from the lower left sternal border. *Tricuspid Regurgitation (TR)* - TR is characterized by a **holosystolic murmur** that increases with inspiration, heard at the left lower sternal border. - It typically causes a prominent **"v" wave** in the jugular venous pulse due to regurgitant flow into the right atrium, not a prominent "a" wave. *Pulmonary Stenosis (PS)* - PS presents with a **systolic ejection murmur** at the left upper sternal border (pulmonic area), not a diastolic murmur. - While it can cause right heart strain, it does not produce the characteristic middiastolic murmur or prominent "a" wave seen in tricuspid stenosis.

Q: A patient presents with confusion, altered mental status, and unusual behavior. On examination, CNS features such as disorientation and lethargy are noted. Laboratory results reveal a urine osmolality of 1000 mOsm/kg and a plasma osmolality of 250 mOsm/kg. What is the most likely electrolyte imbalance?

Hyponatremia. ***Hyponatremia*** - The **low plasma osmolality** (250 mOsm/kg) combined with a **high urine osmolality** (1000 mOsm/kg) indicates that the kidneys are inappropriately concentrating urine despite diluted plasma, a hallmark finding in euvolemic hyponatremia. - **Confusion**, **altered mental status**, and **unusual behavior** are classic neurological symptoms associated with hyponatremia, particularly when it develops acutely or severely. *Hypokalemia* - **Hypokalemia** is characterized by low serum potassium and can cause muscle weakness, arrhythmias, and fatigue, but it does not directly explain the given plasma and urine osmolality findings. - The neurological symptoms described are not typical primary manifestations of hypokalemia. *Hyperkalemia* - **Hyperkalemia** involves high serum potassium, commonly leading to cardiac arrhythmias and muscle weakness. - The provided **osmolality values** are not consistent with a primary diagnosis of hyperkalemia. *Hypernatremia* - **Hypernatremia** is defined by high serum sodium and would present with **high plasma osmolality**, which contradicts the given plasma osmolality of 250 mOsm/kg. - While it can cause neurological symptoms, the osmolality findings rule it out. *Hypercalcemia* - **Hypercalcemia** can present with neurological symptoms including confusion and lethargy ("stones, bones, groans, and psychiatric overtones"). - However, hypercalcemia does not produce the characteristic **low plasma osmolality with high urine osmolality** pattern seen in this case.

Q: 30-year-old male, weighing 70 kg , presents with a serum sodium level of $120 \mathrm{mEq} / \mathrm{L}$. Calculate the total sodium deficit.

840 mEq. ***840 mEq*** - The formula for calculating **total sodium deficit** is: **(Desired Na - Actual Na) × Total Body Water (TBW)**. - In a male, TBW is approximately **60% of body weight**. For a 70 kg male, **TBW = 0.6 × 70 kg = 42 L**. - With a desired sodium of **140 mEq/L** (normal) and actual sodium of **120 mEq/L**, the total deficit is: - **(140 - 120) × 42 = 20 × 42 = 840 mEq** - This represents the **complete calculated sodium deficit** needed to restore serum sodium to normal levels. - **Note:** In clinical practice, this entire deficit is NOT replaced rapidly. Typically, only **6-12 mEq/L increase per 24 hours** is recommended to prevent **osmotic demyelination syndrome**, but the question asks for the total calculated deficit. *630 mEq* - This value represents a **partial correction target**, corresponding to raising serum sodium to approximately **135 mEq/L** instead of 140 mEq/L: (135 - 120) × 42 = 630 mEq. - Alternatively, it equals about **75% of the total deficit** (840 × 0.75 = 630). - While this may reflect a practical clinical target, it does not answer the question which asks for the **total deficit**. *420 mEq* - This corresponds to raising serum sodium by **10 mEq/L** (10 × 42 = 420 mEq). - This represents the **maximum recommended increase in the first 24 hours** to prevent complications. - It is a safe initial correction amount but not the total calculated deficit. *280 mEq* - This represents an even smaller increment, roughly equivalent to raising serum sodium by **6-7 mEq/L**. - This would be an **ultra-conservative initial correction** for chronic hyponatremia. - It significantly underestimates the total sodium deficit. *1260 mEq* - This is an **overestimation** that might result from incorrectly using 100% body weight as TBW instead of 60%: (140 - 120) × 70 = 1400 mEq (close to this range). - Or from miscalculation using wrong formula components. - This exceeds the actual total sodium deficit.

Q: What surgery is shown here in the image?

Thiersch wiring. ***Thiersch wiring*** - The image clearly depicts a **suture or wire** placed circumferentially around the anus to reduce its caliber, which is the hallmark of a **Thiersch procedure**. - This technique is used to treat **anal incontinence** by constricting the anal opening and improving sphincter function. *Hemorrhoidectomy* - This procedure involves the **surgical removal of hemorrhoids** and the images do not show any identifiable hemorrhoidal tissue being excised. - While bleeding and prolapse can be associated with hemorrhoids, the depicted technique with circumferential wiring is not used for their removal. *Altemeier operation* - The Altemeier operation is a type of **perineal rectosigmoidectomy** for rectal prolapse that involves resecting the prolapsed segment of the rectum. - The image does not illustrate resection of rectal tissue; instead, it shows a constricting device around the anus. *Wells procedure* - The Wells procedure, or **rectopexy**, involves anchoring the rectum to the sacrum to correct rectal prolapse. - This procedure typically involves an abdominal approach and fixation techniques, which are not represented in the illustration.

Q: A patient presents with upper limb swelling after undergoing a modified radical mastectomy (MRM). What is the most likely cause?

Upper limb Lymphedema. ***Upper limb Lymphedema*** - **Lymphedema** is a common complication after **modified radical mastectomy (MRM)** due to the removal of axillary lymph nodes and subsequent disruption of lymphatic drainage pathways. - This disruption leads to an accumulation of lymphatic fluid in the interstitial tissues, causing **swelling** in the ipsilateral upper limb. *Angiosarcoma* - **Angiosarcoma** (Stewart-Treves syndrome) is a very rare, aggressive tumor that can occur in the chronic lymphedematous limb after mastectomy. - It presents as multiple **violaceous nodules or plaques** in the affected limb, which is not described as the initial finding. *Recurrence* - **Recurrence** of breast cancer in the axilla or chest wall could cause swelling, but it would typically involve a palpable mass, skin changes, or pain, which are not mentioned as the primary symptom. - While recurrence can lead to lymphatic obstruction, **lymphedema** is a more direct and common post-operative complication. *Metastasis* - **Metastasis** to the axillary or supraclavicular lymph nodes could cause lymphatic obstruction and swelling. - However, lymphedema from direct surgical disruption of lymphatics is a more immediate and common cause of upper limb swelling following MRM, especially without other signs of widespread disease.

Q: Which of the following is the most commonly performed repair for a direct inguinal hernia?

Lichtenstein repair. ***Lichtenstein repair*** - The **Lichtenstein repair** is a **tension-free mesh repair** and is the most commonly performed technique for direct inguinal hernias due to its low recurrence rates. - This technique involves placing a **synthetic mesh** over the deficient posterior wall of the inguinal canal, reinforcing the weakened area. *Bassini's repair* - **Bassini's repair** is a tissue-based repair that involves suturing the conjoined tendon to the inguinal ligament. - It creates tension on the repair, which historically led to **higher recurrence rates** compared to mesh repairs. *Herniotomy* - **Herniotomy** is the surgical removal of the **hernia sac** without repairing the defect in the abdominal wall. - This procedure is typically reserved for **pediatric patients** with indirect inguinal hernias due to the good intrinsic muscle tone and relatively small defect, but it is not the primary repair for direct inguinal hernias in adults. *All of the options* - While all listed procedures are methods for hernia management, only the **Lichtenstein repair** is considered the most commonly performed repair for direct inguinal hernias in current practice. - The other options are less commonly performed or reserved for specific patient populations.

Q: After a total thyroidectomy, the surgeon is unable to extubate the patient, who shows cyanosis and respiratory distress. What is the most likely cause of the inability to extubate?

Bilateral recurrent laryngeal nerve palsy. ***Bilateral recurrent laryngeal nerve palsy*** - After total thyroidectomy, injury to both **recurrent laryngeal nerves** can lead to paralysis of the abductor muscles of the vocal cords causing them to approximate, leading to **airway obstruction**, cyanosis, and respiratory distress. - This condition prevents successful extubation and often necessitates **reintubation** or **tracheostomy**. *Unilateral recurrent laryngeal nerve palsy* - Causes **hoarseness** due to unilateral vocal cord paralysis but typically does not result in severe airway obstruction or inability to extubate. - The unaffected vocal cord can usually compensate sufficiently to maintain an adequate airway for breathing. *Superior laryngeal nerve palsy* - Primarily affects the **protective reflexes of the larynx** and vocal cord tension (pitch), leading to issues like **aspiration risk** and a weak, breathy voice. - It does not directly cause vocal cord paralysis in a position that obstructs the airway. *Hemorrhage* - While a significant **post-operative hemorrhage** in the neck can cause airway compression and respiratory distress, it usually manifests as **neck swelling** and possibly hypovolemic shock. - The scenario explicitly states "inability to extubate," suggesting a vocal cord issue rather than external compression by a hematoma.

Question 1

A patient presents with breathlessness and wheezing. Absolute eosinophil count is 500 cells/ $\mu \mathrm{L}$. Chest X-ray shows a miliary pattern. What is the most likely diagnosis?

Accepted Answer

Tropical pulmonary eosinophilia

Answer

Bronchial asthma

Answer

Miliary Tuberculosis (TB)

Answer

Hypersensitivity pneumonitis

Answer

Allergic bronchopulmonary aspergillosis (ABPA)

Question 2

A patient presents with breathing difficulty and generalized weakness. On auscultation, a middiastolic murmur with a prominent "a" wave is observed. What is the most likely diagnosis?

Accepted Answer

Tricuspid Stenosis (TS)

Answer

Mitral Regurgitation (MR)

Answer

Mitral Stenosis (MS)

Answer

Tricuspid Regurgitation (TR)

Answer

Pulmonary Stenosis (PS)

Question 3

A patient presents with confusion, altered mental status, and unusual behavior. On examination, CNS features such as disorientation and lethargy are noted. Laboratory results reveal a urine osmolality of 1000 mOsm/kg and a plasma osmolality of 250 mOsm/kg. What is the most likely electrolyte imbalance?

Accepted Answer

Hyponatremia

Answer

Hypokalemia

Answer

Hyperkalemia

Answer

Hypernatremia

Answer

Hypercalcemia

Question 4

30-year-old male, weighing 70 kg , presents with a serum sodium level of $120 \mathrm{mEq} / \mathrm{L}$. Calculate the total sodium deficit.

Accepted Answer

840 mEq

Answer

630 mEq

Answer

280 mEq

Answer

420 mEq

Answer

1260 mEq

Question 5

A patient with hypertension, peripheral edema, and chronic kidney disease (CKD) presents for management. Which of the following medications would be the best choice?

Accepted Answer

Chlorthalidone

Answer

Aliskiren

Answer

Beta blocker

Answer

Prazosin

Answer

Furosemide

Question 6

What surgery is shown here in the image?

Accepted Answer

Thiersch wiring

Answer

Hemorrhoidectomy

Answer

Altemeier operation

Answer

Wells procedure

Question 7

A patient presents with upper limb swelling after undergoing a modified radical mastectomy (MRM). What is the most likely cause?

Accepted Answer

Upper limb Lymphedema

Answer

Angiosarcoma

Answer

Recurrence

Answer

Metastasis

Question 8

Which of the following is the most commonly performed repair for a direct inguinal hernia?

Accepted Answer

Lichtenstein repair

Answer

Bassini's repair

Answer

Herniotomy

Answer

All of the options

Question 9

A patient presents with breathlessness and decreased air entry into the right lung following a road traffic accident (RTA) and is hypotensive. What is the next step in management?

Accepted Answer

Needle insertion at 2nd ICS in midclavicular line (MCL)

Answer

Wide bore needle decompression

Answer

Needle insertion at 5th ICS in mid-axillary line

Answer

Fluid resuscitation using wide bore cannula

Question 10

After a total thyroidectomy, the surgeon is unable to extubate the patient, who shows cyanosis and respiratory distress. What is the most likely cause of the inability to extubate?

Accepted Answer

Bilateral recurrent laryngeal nerve palsy

Answer

Unilateral recurrent laryngeal nerve palsy

Answer

Superior laryngeal nerve palsy

Answer

Hemorrhage

NEET-PG 2021

Internal Medicine

Pharmacology

Surgery