Endocrine Regulation of Metabolism Practice Questions

Question 1

Which of the following statements best describes the mechanism of action of insulin on target cells?

Accepted Answer

Insulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

Answer

Insulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

Answer

Insulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

Answer

Insulin enters the cell and causes the release of calcium ions from intracellular stores.

Question 2

Metabolic changes seen in starvation include all of the following except?

Accepted Answer

Increased glycolysis

Answer

Ketogenesis

Answer

Protein degradation

Answer

Increased gluconeogenesis

Question 3

All of the following are increased in Acute stress except

Accepted Answer

Insulin

Answer

Growth hormone

Answer

Epinephrine

Answer

Glucagon

Question 4

All are true about hormone functions except:

Accepted Answer

Cortisol regulates plasma volume

Answer

Thyroid hormones regulate metabolism

Answer

ADH regulates blood osmolality

Answer

Insulin regulates blood glucose

Question 5

Which of the following enzyme activity decreases in fasting?

Accepted Answer

Phosphofructokinase I

Answer

Hormone sensitive lipase

Answer

Glycogen phosphorylase

Answer

Acetyl CoA Carboxylase

Question 6

All of these cause hyperglycemia except:

Accepted Answer

Insulin

Answer

Catecholamines

Answer

Cortisol

Answer

GH

Question 7

Which of the following hormones are under inhibitory control of hypothalamus?

Accepted Answer

Both prolactin and growth hormone

Answer

Growth hormone only

Answer

Prolactin only

Answer

Neither prolactin nor growth hormone

Question 8

Hyperthyroid state is characterized by -

Accepted Answer

Lipolysis

Answer

Decreased glycolysis

Answer

Increased cholesterol

Answer

Increased protein synthesis

Question 9

Which of the following inhibit gonadotropin-releasing hormone pulse secretion?

Accepted Answer

Prolactin

Answer

Oxytocin

Answer

Thyroxine

Answer

Insulin

Question 10

Insulin-like growth factor is secreted by:

Accepted Answer

Liver

Answer

Pituitary gland

Answer

Pancreas

Answer

Adrenal glands

Endocrine Regulation of Metabolism — MCQs

Endocrine Regulation of Metabolism — MCQs

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