Biotransformation and Metabolism Pathways — MCQs

The cytochrome involved in monooxygenase-mediated detoxification of drugs is:

What is the primary role of Cytochrome P450 enzymes in the liver?

Which is true for glucuronidation:

A factor that is likely to increase the duration of action of a drug that is partially metabolized by CYP3A4 in the liver is:

All are true for cytochrome P450 enzymes EXCEPT:

A patient on warfarin has a high INR. Which drug likely caused this?

Which of the following drugs is known to have low first pass metabolism?

Which substance is conjugated in the liver and is the final product of heme catabolism?

Bile salts undergo conjugation for enhanced solubility:

Which of the following statements about the biodisposition of penicillins and cephalosporins is NOT accurate?