Pharmacotherapy in Children Practice Questions

Question 1

For a child 3-5 months of age with H1N1, treatment Oseltamivir dose is

Accepted Answer

20 mg BD X 5 days

Answer

12 mg BD X 5 days

Answer

25 mg BD X 5 days

Answer

20 mg OD X 5 days

Question 2

What is the effect of indomethacin on the ductus arteriosus?

Accepted Answer

Closure of the ductus in premature neonates

Answer

Patent ductus arteriosus

Answer

Closure of the ductus in term and premature neonates

Answer

Closure of the ductus in older children

Question 3

Which pharmacokinetic change commonly occurs in geriatric patients?

Accepted Answer

Renal clearance

Answer

Gastric absorption

Answer

Liver metabolism

Answer

Hypersensitivity

Question 4

Gray baby syndrome is caused by which of the following drugs?

Accepted Answer

Chloramphenicol

Answer

Chlorpromazine

Answer

Phenytoin

Answer

Gentamycin

Question 5

What is the mechanism by which phenobarbital and metalloporphyrin act respectively to reduce bilirubin levels in neonatal jaundice?

Accepted Answer

Induce bilirubin conjugation by UDP Glucuronyltransferase and competitive inhibition of hemeoxygenase

Answer

Enhance secretion of conjugated bilirubin and induce bilirubin conjugation by UDP Glucuronyltransferase

Answer

Induce bilirubin conjugation by UDP Glucuronyltransferase and enhance secretion of conjugated bilirubin

Answer

Competitive inhibition of hemeoxygenase and enhance secretion of conjugated bilirubin

Question 6

Most common cause of Mobius syndrome is the use of which of the following drugs in pregnancy?

Accepted Answer

Misoprostol

Answer

Thalidomide

Answer

Methotrexate

Answer

Dinoprostone

Question 7

An elderly male patient has presented with recurrent falls. Which of the following medicines is most likely responsible?

Accepted Answer

Prazosin

Answer

Metformin

Answer

Acarbose

Answer

Thiazides

Question 8

Which of the following drugs should be avoided in a 7-year-old child?

Accepted Answer

Ofloxacin

Answer

Cefixime

Answer

Erythromycin

Answer

Amoxicillin

Question 9

What is the most dangerous effect of belladonna in very young children?

Accepted Answer

Hyperthermia

Answer

Dehydration

Answer

Hallucination

Answer

Hypertension

Question 10

Which of the following antiglaucoma medications is unsafe in infants?

Accepted Answer

Brimonidine

Answer

Timolol

Answer

Latanoprost

Answer

Dorzolamide

Pharmacotherapy in Children — MCQs

Pharmacotherapy in Children — MCQs

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