Antifungal Agents Practice Questions

Question 1

Which of the following antifungal agents is used in combination therapy for cryptococcal meningitis?

Accepted Answer

Flucytosine

Answer

Nystatin

Answer

Terbinafine

Answer

Voriconazole

Question 2

Which of the following is not a part of P. versicolor treatment -

Accepted Answer

Griseofulvin

Answer

Selenium sulfide

Answer

Clotrimazole

Answer

Ketoconazole

Question 3

Amphotericin B acts on:-

Accepted Answer

Cell membrane

Answer

Cytoplasm

Answer

Nucleus

Answer

Cell wall

Question 4

Which drug should not be given with ketoconazole?

Accepted Answer

Indinavir

Answer

Macrolide

Answer

All of the options

Answer

Aminoglycoside

Question 5

Which of the following statements about Ciclesonide is incorrect?

Accepted Answer

Oral candidiasis is common with its use.

Answer

It is a prodrug activated by bronchial esterase.

Answer

It has comparable efficacy to other inhalational corticosteroids.

Answer

It has fewer side effects than other inhalational corticosteroids.

Answer

It has low systemic bioavailability due to extensive first-pass metabolism.

Question 6

All of the following drugs cause renal failure except?

Accepted Answer

Cefoperazone

Answer

Amphotericin B

Answer

Gentamicin

Answer

Cephaloridine

Question 7

What is the primary advantage of the newer liposomal preparation of amphotericin B?

Accepted Answer

Reduced nephrotoxicity.

Answer

Lower tissue uptake in the kidneys.

Answer

Similar efficacy and antifungal spectrum as conventional preparations.

Answer

All of the above

Question 8

Which of the following combinations can result in severe toxicity due to inhibition of cytochrome P450 enzymes?

Accepted Answer

Atorvastatin + Itraconazole

Answer

Amiodarone + Atorvastatin

Answer

Carbamazepine + Atorvastatin

Answer

Phenytoin + Atorvastatin

Question 9

Emtricitabine is a/an:

Accepted Answer

Nucleoside reverse transcriptase inhibitor (NRTI)

Answer

Alkylating agent

Answer

Mitotic inhibitor

Answer

None of the options

Question 10

Griseofulvin is not useful in one of the following

Accepted Answer

Tinea versicolor

Answer

Tinea capitis

Answer

Tinea pedis

Answer

Tinea cruris

Antifungal Agents — MCQs

Antifungal Agents — MCQs

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