Topoisomerase Inhibitors — MCQs

Many drugs are used as rescue therapy for preventing the adverse effects of anticancer drugs. Folinic acid is used in:-

A woman presenting with symptoms of urinary tract infection was prescribed a drug that causes tendon rupture and arthropathy. What is the mechanism of action of the drug?

Which enzyme is required for cutting the DNA strand during synthesis?

During the treatment of chronic myeloid leukemia, cytogenetic remission is least likely to occur with which one of the following treatment modalities?

All are true regarding Sunitinib except which of the following?

The use of which of the following helps in reducing the toxicity of doxorubicin to the heart?

Which is the most cardiotoxic anti-cancer drug among the following?

Mechanism of action of Pemetrexed is:-

All of the following are hormonal agents used in treatment of cancer EXCEPT:

Which local anesthetic is considered the most cardiotoxic?