Immunotherapy — MCQs

Adverse reactions following whole cell pertussis immunization include:

An example of an IMiD (immunomodulatory derivative of thalidomide) is:

Omalizumab is primarily used in the treatment of which condition?

In chronic allergy, which Ig is more persistent in the body?

Which is the best investigation to confirm diagnosis of anaphylaxis?

IV dose of 1:10,000 concentration of epinephrine in a 2 kg preterm baby is:

A 2.5-year-old boy is brought to the nutrition clinic. He was born at term with a birth weight of 3.0 kg. His mother reports that since weaning he has been fed almost exclusively on a maize-based porridge with minimal animal protein or legumes. On examination, he weighs 9.8 kg and has a height of 82 cm. He has bilateral pitting oedema up to the ankles, generalised skin changes with areas of hyperpigmentation and hypopigmentation, and hair that shows alternating light and dark bands. Serum albumin is 1.8 g/dL. Haemoglobin is 8.2 g/dL. Stool microscopy shows no parasites. Which of the following biochemical profiles is most consistent with this child's nutritional disorder?

What is a characteristic feature of Systemic Juvenile Idiopathic Arthritis?

An 8-year-old child has had abdominal pain and dark urine for 10 days. Physical examination shows blotchy purple skin lesions on the trunk and extremities. Urinalysis shows hematuria and proteinuria. Serologic test results are negative for myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA). A skin biopsy specimen shows necrotizing vasculitis of small dermal vessels. A renal biopsy specimen shows immune complex deposition in glomeruli, with some IgA-rich immune complexes. Which of the following is the most likely diagnosis?

A child presents with delayed separation of the umbilical cord, leukocytosis, Down syndrome, and recurrent infections. What is the most likely diagnosis?