Failure to Thrive Due to Neglect — MCQs
A 5-year-old has the following anthropometry findings: Weight/age < -3.2 SD, Height/age < -2.5 SD, Weight/height < -1.7 SD. What is the most likely diagnosis?
Which of the following anthropometric indicators best reflects acute malnutrition (wasting) in children?
What is the true statement regarding an 'at-risk baby'?
Which of the following findings is LEAST likely to be associated with battered child syndrome?
Which is true about an infant with failure to thrive and the following findings?
A 16-year-old girl comes to a doctor with fractured forearm. She said she tripped and fell but cigarette burns were observed on her forearm. What will be your next step?
Which of the following is not typically associated with enlarged adenoids?
Which of the following is NOT a feature of HIV infection in childhood -
A child presented at 10 weeks with recurrent episode of pneumonia and failure to thrive. X-ray shows cardiomegaly & pulmonary plethora. What is the diagnosis?
A 1-month old baby present with frequent vomiting and failure to thrive. There are features of moderate dehydration. Blood sodium in 122 mEq/l and potassium is 6.1 mEq/l. The most likely diagnosis is?
Failure to Thrive Due to Neglect Indian Medical PG Practice Questions and MCQs
Question 1: A 5-year-old has the following anthropometry findings: Weight/age < -3.2 SD, Height/age < -2.5 SD, Weight/height < -1.7 SD. What is the most likely diagnosis?
- A. Moderate acute malnutrition
- B. Chronic malnutrition
- C. Severe Acute Malnutrition
- D. Severe Acute Malnutrition with stunting (Correct Answer)
Explanation: ***Severe Acute Malnutrition with stunting*** - This child has **both acute and chronic malnutrition** indicators that must be identified together for accurate diagnosis and management. - **Height-for-age < -2.5 SD** confirms **stunting (chronic malnutrition)**, indicating long-term nutritional deprivation. - **Weight-for-age < -3.2 SD** indicates **severe underweight**, which in the context of stunting reflects the combined impact of both chronic and acute malnutrition. - **Weight-for-height < -1.7 SD** shows mild wasting, indicating an acute component, though not meeting the < -3 SD threshold for SAM by W/H alone. - The combination of severe underweight, stunting, and wasting requires the comprehensive diagnosis of **SAM with stunting** for appropriate clinical management and nutritional rehabilitation. *Severe Acute Malnutrition (without mentioning stunting)* - While this child has severe underweight, diagnosing only SAM **ignores the documented stunting** (H/A < -2.5 SD). - SAM is typically defined by **Weight-for-height < -3 SD**, but this child's W/H is only -1.7 SD, not meeting the strict SAM criteria by this parameter alone. - In pediatric nutrition, when stunting coexists with severe underweight, both components must be identified as they have different management implications. *Moderate acute malnutrition* - Moderate acute malnutrition requires **Weight-for-height between -2 SD and -3 SD** or MUAC between 11.5-12.5 cm. - This child's W/A is **< -3.2 SD** (severe underweight, not moderate), making this diagnosis inadequate. - The presence of stunting and severe underweight indicates a more serious condition than moderate acute malnutrition. *Chronic malnutrition* - While **Height-for-age < -2.5 SD confirms chronic malnutrition (stunting)**, this diagnosis alone doesn't capture the full clinical picture. - The **Weight-for-age < -3.2 SD** indicates severe underweight with an acute wasting component, requiring urgent intervention beyond addressing chronic malnutrition alone. - A diagnosis of only "chronic malnutrition" would underestimate the severity and miss the acute component requiring immediate management.
Question 2: Which of the following anthropometric indicators best reflects acute malnutrition (wasting) in children?
- A. Weight for height (Correct Answer)
- B. Height for age
- C. BMI for age
- D. Weight for age
Explanation: ***Weight for height*** - **Weight for height** directly measures a child's **current weight** relative to their **height**, providing a snapshot of their nutritional status. - A low weight for height indicates **wasting**, which is a sign of **acute malnutrition** resulting from recent or rapid weight loss. *Height for age* - **Height for age** measures the child's **height** relative to standard measurements for children of the same age. - A low height for age indicates **stunting**, which is a chronic nutritional problem reflecting **long-term malnutrition**. *BMI for age* - **BMI for age** can be used as an indicator for both **underweight** and **overweight** in children over 2 years of age. - While it reflects nutritional status, **weight-for-height** is generally considered a more direct and sensitive indicator for **acute malnutrition** (wasting) in young children. *Weight for age* - **Weight for age** measures the overall nutritional status by comparing a child's **weight** to that of a reference population of the same age. - It reflects both **acute and chronic malnutrition** (underweight) but cannot distinguish between wasting and stunting alone.
Question 3: What is the true statement regarding an 'at-risk baby'?
- A. Mild malnutrition with weight slightly below expected norms.
- B. Socioeconomic risk due to high birth order (more than 3). (Correct Answer)
- C. Normal birth weight above the critical threshold of 2.5 kg.
- D. Severe malnutrition with weight significantly below expected norms.
Explanation: ***Socioeconomic risk due to high birth order (more than 3).*** - An **"at-risk baby"** is defined by specific criteria that identify infants vulnerable to adverse health outcomes during the neonatal and early infantile period. - **High birth order (>3)** is a recognized risk factor as per IAP (Indian Academy of Pediatrics) and WHO guidelines, primarily due to: - **Maternal depletion syndrome** (depleted maternal nutritional reserves from multiple pregnancies) - **Socioeconomic constraints** (limited resources spread across more children) - **Reduced parental attention** and care per child - Other criteria for "at-risk baby" include: birth weight <2.5 kg, preterm birth, birth asphyxia, congenital anomalies, and maternal risk factors. *Severe malnutrition with weight significantly below expected norms.* - This describes **severe acute malnutrition (SAM)** in an infant or child, which is a **nutritional disorder**, not a defining criterion of an "at-risk baby" at birth. - While malnutrition increases morbidity risk, the term "at-risk baby" specifically refers to **perinatal and neonatal risk factors** present at or around the time of birth. - SAM is a **consequence** that may develop later, rather than a defining characteristic of the "at-risk" classification. *Mild malnutrition with weight slightly below expected norms.* - **Mild malnutrition** is not a criterion for classifying a baby as "at-risk" in the standard pediatric definition. - The "at-risk baby" classification focuses on **specific measurable risk factors** (birth weight, gestational age, birth order, etc.) rather than mild nutritional deviations. *Normal birth weight above the critical threshold of 2.5 kg.* - A **normal birth weight (≥2.5 kg)** is actually a **protective factor** and indicates lower risk at birth. - This statement describes a baby who does **not meet the "at-risk" criteria** based on birth weight, though other risk factors could still be present. - Birth weight ≥2.5 kg is one indicator of adequate intrauterine growth and lower neonatal mortality risk.
Question 4: Which of the following findings is LEAST likely to be associated with battered child syndrome?
- A. Subdural hematoma
- B. Skin bruising
- C. Failure to thrive (Correct Answer)
- D. Multiple fractures in different stages of healing
Explanation: ***Failure to thrive*** - While **neglect** can lead to failure to thrive, it is **less directly indicative** of battered child syndrome compared to specific traumatic injuries - Failure to thrive reflects **chronic malnutrition and inadequate care** rather than acute physical abuse - Battered child syndrome primarily involves **physical trauma** (fractures, bruises, head injuries) rather than growth deficiencies - Of all the options, this finding is **LEAST characteristic** of direct physical battering *Subdural hematoma* - **Highly associated** with battered child syndrome, particularly in **abusive head trauma** (shaken baby syndrome) - Results from tearing of bridging veins due to violent shaking or impact - One of the most serious manifestations of physical abuse in children *Skin bruising* - The **most common visible sign** of physical abuse in children - Multiple bruises in **different stages of healing** and in unusual locations (face, neck, trunk, buttocks) are highly suspicious - Pattern bruising (hand prints, belt marks, loop marks) is pathognomonic of abuse *Multiple fractures in different stages of healing* - **Classic radiologic finding** in battered child syndrome - Metaphyseal corner fractures and posterior rib fractures are particularly specific for abuse - Different stages of healing indicate repeated episodes of trauma
Question 5: Which is true about an infant with failure to thrive and the following findings?
- A. Hypokalemia
- B. Metabolic alkalosis
- C. Increased urinary sodium (Correct Answer)
- D. Increased cortisol
Explanation: ***Increased urinary sodium*** - This image displays an infant with **ambiguous genitalia**, specifically severe clitoromegaly. This is a classic presentation of **congenital adrenal hyperplasia (CAH)** due to **21-hydroxylase deficiency**. - In salt-wasting CAH, deficient **aldosterone** production leads to **renal sodium loss**, resulting in increased urinary sodium, **hyponatremia**, and **hypotension**, contributing to failure to thrive. *Hypokalemia* - **Hypokalemia** is not typically seen in salt-wasting CAH; rather, **hyperkalemia** is more common due to the lack of aldosterone's mineralocorticoid effect, which normally promotes potassium excretion. - The absence of aldosterone causes sodium to be excreted and potassium to be retained. *Metabolic alkalosis* - **Metabolic alkalosis** is not characteristic of salt-wasting CAH; instead, these infants often develop **metabolic acidosis** due to the loss of sodium bicarbonate and impaired acid excretion. - The primary electrolyte disturbance points towards acidosis, not alkalosis. *Increased cortisol* - In 21-hydroxylase deficiency, the enzyme responsible for converting precursors to **cortisol** and aldosterone is deficient, leading to **decreased cortisol** production. - The adrenal glands instead shunt precursors towards androgen synthesis, causing **adrenal hyperplasia** and the virilization seen in the image.
Question 6: A 16-year-old girl comes to a doctor with fractured forearm. She said she tripped and fell but cigarette burns were observed on her forearm. What will be your next step?
- A. To tell or discuss with colleagues that she is a case of abuse
- B. To inform higher authorities
- C. To do a complete physical examination (Correct Answer)
- D. To call local social worker for help
Explanation: ***To do a complete physical examination*** - A comprehensive **physical examination** is essential to assess the full extent of injuries and to identify any other signs of abuse that might not be immediately apparent. - This step ensures that all medical needs are addressed and that any potential harm is documented appropriately within the medical record. *To tell or discuss with colleagues that she is a case of abuse* - While suspicion of abuse is high, immediately labeling the patient as a "case of abuse" to colleagues without further assessment can be premature and may compromise patient confidentiality. - Discussing with colleagues should follow a thorough examination and be part of a structured approach to **interprofessional collaboration** once concerns are medically substantiated. *To inform higher authorities* - Reporting to higher authorities is a critical step in cases of suspected abuse, but it typically follows a **thorough medical evaluation** and documentation of findings. - Informing authorities prematurely without a complete medical assessment could lead to incomplete information and potentially delay necessary medical care for the patient. *To call local social worker for help* - Involving a social worker is an important component of managing suspected child abuse, as they can provide support and guidance for the patient and family. - However, the immediate priority is to address the patient's medical needs and gather medical evidence through a **complete physical examination** before initiating social services.
Question 7: Which of the following is not typically associated with enlarged adenoids?
- A. Otitis media
- B. Nasal obstruction
- C. Failure to thrive of child
- D. Esophagitis (Correct Answer)
Explanation: ***Esophagitis*** - **Enlarged adenoids** are localized to the **nasopharynx** and do not directly impact the esophagus, making esophagitis an unlikely direct complication. - While chronic mouth breathing from enlarged adenoids can lead to **dry mouth**, it is not a direct cause of esophageal inflammation. *Otitis media* - Enlarged adenoids can obstruct the **eustachian tubes**, which connect the middle ear to the nasopharynx, predisposing to **recurrent acute otitis media** or **otitis media with effusion**. - This obstruction impairs middle ear ventilation and drainage, facilitating bacterial growth and inflammation. *Nasal obstruction* - Enlarged adenoids directly block the **nasopharyngeal airway**, leading to chronic **nasal obstruction** and obligate mouth breathing. - This can cause symptoms like snoring, sleep-disordered breathing, and a characteristic "adenoid facies." *Failure to thrive of child* - **Severe nasal obstruction** from enlarged adenoids can disrupt feeding, particularly in infants, as they must breathe through their mouths while attempting to feed. - This compromised feeding, along with **sleep apnea**, increases energy expenditure and can collectively contribute to **failure to thrive**.
Question 8: Which of the following is NOT a feature of HIV infection in childhood -
- A. Failure to thrive
- B. Hepatomegaly
- C. Kaposi sarcoma (Correct Answer)
- D. Lymphoid interstitial pneumonitis
Explanation: ***Kaposi sarcoma*** - While Kaposi's sarcoma is a common HIV-associated malignancy in adults, it is **very rare in HIV-infected children**. - Its presence in children with HIV usually suggests a **more aggressive and rapidly progressing disease course**, but it is not a typical or common feature. *Failure to thrive* - **Failure to thrive** is a very common manifestation of HIV infection in children, often due to **poor nutrient absorption**, increased metabolic demands, and chronic infections. - It leads to **poor weight gain and growth faltering**, negatively impacting overall development. *Hepatomegaly* - **Hepatomegaly**, or an enlarged liver, is a frequent finding in HIV-infected children due to various causes such as **opportunistic infections**, drug side effects, and direct HIV involvement of the liver. - It can be a clinical sign indicating **inflammation or dysfunction** of the liver. *Lymphoid interstitial pneumonitis* - **Lymphoid interstitial pneumonitis (LIP)** is a prevalent pulmonary complication specific to HIV infection in children, characterized by **lymphocytic infiltration of the alveolar septa and peribronchial spaces**. - It often leads to **chronic cough**, hypoxemia, and is considered an **AIDS-defining condition** in pediatric HIV.
Question 9: A child presented at 10 weeks with recurrent episode of pneumonia and failure to thrive. X-ray shows cardiomegaly & pulmonary plethora. What is the diagnosis?
- A. VSD (Correct Answer)
- B. TOF
- C. Patent foramen ovale
- D. ASD
Explanation: ***VSD*** - **Ventricular septal defect (VSD)** is the most common cause of this presentation in early infancy (symptoms typically appear at **6-10 weeks** of age). - Large VSDs cause significant **left-to-right shunt** leading to pulmonary overcirculation, resulting in **recurrent pneumonia** and **failure to thrive**. - **Cardiomegaly** (due to volume overload of left atrium and ventricle) and **pulmonary plethora** (increased pulmonary vascular markings) on X-ray are classic findings. - The infant may also present with tachypnea, feeding difficulties, and poor weight gain. *TOF* - **Tetralogy of Fallot (TOF)** is a **cyanotic heart defect** with right-to-left shunt, presenting with cyanosis and hypoxic spells, not recurrent pneumonia. - X-ray shows **boot-shaped heart** and **pulmonary oligemia** (decreased pulmonary vascular markings), not pulmonary plethora. - Does not typically cause failure to thrive in the same manner as acyanotic left-to-right shunt lesions. *Patent foramen ovale* - A **patent foramen ovale (PFO)** is a normal variant in infants and typically remains **asymptomatic**. - Does not cause significant hemodynamic shunting in the absence of elevated right atrial pressure. - Does not cause **cardiomegaly**, **pulmonary plethora**, recurrent pneumonia, or failure to thrive. *ASD* - An **atrial septal defect (ASD)** also causes left-to-right shunt with pulmonary plethora, but the shunt develops **gradually** over time. - ASD typically presents **later in childhood or adulthood** with milder symptoms (fatigue, exercise intolerance) due to lower pressure gradient across atria. - **Recurrent pneumonia and failure to thrive at 10 weeks** are uncommon with isolated ASD, as the hemodynamic changes are less pronounced in early infancy compared to VSD. - When symptomatic in infancy, large ASDs present later (around 6 months to 1 year) rather than at 10 weeks.
Question 10: A 1-month old baby present with frequent vomiting and failure to thrive. There are features of moderate dehydration. Blood sodium in 122 mEq/l and potassium is 6.1 mEq/l. The most likely diagnosis is?
- A. 11β-hydroxylase deficiency
- B. 21-hydroxylase deficiency (Correct Answer)
- C. Gitelman syndrome
- D. Bartter syndrome
Explanation: ***21-hydroxylase deficiency*** - This condition presents in infancy with **salt-wasting adrenal crisis** due to impaired cortisol and aldosterone synthesis, leading to **hyponatremia**, **hyperkalemia**, **dehydration**, and **vomiting**. - The deficiency in 21-hydroxylase blocks the synthesis of **aldosterone**, causing sodium loss and potassium retention, consistent with the electrolyte abnormalities. *11β-hydroxylase deficiency* - This deficiency causes an accumulation of **11-deoxycorticosterone (DOC)**, which has mineralocorticoid activity, leading to **hypertension** and **hypokalemia**, rather than hyponatremia and hyperkalemia. - While it can cause virilization, the electrolyte imbalance is distinctly different from the case presented. *Gitelman syndrome* - This is a **renal tubulopathy** characterized by reabsorptive defects in the distal convoluted tubule, leading to **hypokalemia**, **metabolic alkalosis**, **hypomagnesemia**, and **hypocalciuria**. - It would not typically present with severe hyponatremia or hyperkalemia in a neonate with salt wasting. *Bartter syndrome* - This is a **renal tubulopathy** affecting the thick ascending limb of the loop of Henle, resulting in significant salt loss, **hypokalemia**, **metabolic alkalosis**, and **hypercalciuria**. - Like Gitelman syndrome, it is associated with hypokalemia, which contradicts the hyperkalemia seen in the patient.
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