Cervical Pathology and Neoplasia Practice Questions

Question 1

Which condition does NOT increase the risk of cervical cancer?

Accepted Answer

Nulliparity

Answer

Multiple sexual partners

Answer

HPV infection

Answer

Smoking

Question 2

Which HPV oncoprotein initiates cervical carcinogenesis primarily by inactivating the p53 tumor suppressor?

Accepted Answer

E6

Answer

E3

Answer

E5

Answer

E7

Question 3

All are causes of prolapse of cervix EXCEPT:

Accepted Answer

Regular exercise

Answer

Menopause

Answer

Chronic cough

Answer

Delivery of a big baby

Question 4

A 16-year-old girl, not sexually active, came for vaccination against cervical cancer. Which vaccine should be given?

Accepted Answer

Gardasil

Answer

Biovac

Answer

Rubavac

Answer

Tdap

Question 5

Lining epithelium of vagina is

Accepted Answer

Squamous epithelium

Answer

Columnar epithelium

Answer

Transitional epithelium

Answer

Secretory epithelium

Question 6

A cervical Pap smear report stating that "koilocytic atypia is present" indicates the presence of:

Accepted Answer

Cytologic changes caused by human papillomavirus (HPV)

Answer

Cytologic changes caused by herpes simplex virus (HSV)

Answer

High-grade cervical intraepithelial neoplasia (CIN)

Answer

Cytologic changes caused by chlamydial infection

Question 7

Which statement is TRUE regarding the relationship between HPV vaccination and cervical cancer screening?

Accepted Answer

Screening recommendations are currently the same regardless of vaccination status

Answer

Vaccinated women require less frequent screening than unvaccinated women

Answer

HPV vaccination eliminates the need for cervical cancer screening

Answer

Screening should begin at a younger age in vaccinated women

Question 8

How do high-risk HPV types contribute to cervical carcinogenesis?

Accepted Answer

By integration into host genome and expression of E6/E7 oncoproteins

Answer

Through direct mutagenic effects on host DNA

Answer

Through chronic inflammation and oxidative damage

Answer

By inducing apoptosis resistance through capsid proteins

Question 9

Absence of differentiation is known as:-

Accepted Answer

Anaplasia

Answer

Dysplasia

Answer

Metaplasia

Answer

Hyperplasia

Question 10

Anaplasia is

Accepted Answer

Lack of differentiation

Answer

Changing one type of epithelium to another

Answer

Nuclear chromatin

Answer

Morphological changes

Cervical Pathology and Neoplasia — MCQs

Cervical Pathology and Neoplasia — MCQs

Want unlimited practice?