Neoplasia — MCQs

Cytogenetic studies in a 40-year-old woman with follicular lymphoma demonstrate a t(14;18) chromosomal translocation involving the bcl-2 gene. Constitutive expression of the protein encoded by the bcl-2 gene inhibits which of the following processes in this patient's transformed lymphocytes?

Which of the following is a metastasis suppressor gene in relation to prostate cancer?

Arrange the following steps in oncogenesis in the correct sequence:

What is the major contributor to cachexia in advanced cancer?

Which of the following statements regarding the PTEN gene is NOT true?

Which of the following is the most chemoresistant tumor?

A 55-year-old man presents with a solitary breast mass, and biopsy reveals malignant cells. Immunohistochemical staining shows that the tumor cells are positive for estrogen receptor (ER) and negative for Her2/neu. What is the most likely diagnosis?

Which of the following is NOT an oncogenic virus?

Which of the following is not considered a pre-malignant condition at some site?

All of the following are examples of round cell tumors, except?