Neoplasia — MCQs

Malignancy is typically associated with disordered differentiation and maturation. Which of the following best describes anaplasia?

All of the following genes are implicated in colon carcinoma by the classical pathway except?

A man presents with cervical adenopathy. What is the most likely diagnosis?

Which of the following tumors is associated with BRAF mutation?

Which of the following is true regarding sarcomas?

A 58-year-old woman with colon cancer presents with 3 months of increasing shortness of breath. A chest X-ray reveals numerous, bilateral, round masses in both lungs. Histologic examination of an open-lung biopsy discloses malignant gland-like structures, which are nearly identical to the colon primary. Which of the following changes in cell behavior was the first step in the process leading to tumor metastasis from the colon to the lung in this patient?

Defective DNA repair is seen in all of the following conditions EXCEPT?

Post-transplant lymphoma occurs due to proliferation of which of the following cells?

Apoptosis is inhibited by which of the following?

Gleason's score is used for?