Carbapenem-Resistant Enterobacteriaceae Practice Questions

Question 1

All are true about ESBL except -

Accepted Answer

Resistant to carbapenems

Answer

Classification is based on 3rd generation cephalosporin sensitivity

Answer

Cephalosporin sensitivity testing is required to confirm ESBL

Answer

Ambler classification is based on molecular structure

Question 2

Which of the following is NOT a mechanism of antibiotic resistance?

Accepted Answer

Increased drug absorption

Answer

Efflux pump activity

Answer

Inactivation by enzymes such as beta-lactamase

Answer

Modification of drug target sites

Question 3

Carbapenem which has a tendency to cause maximum seizures?

Accepted Answer

Imipenem

Answer

Ertapenem

Answer

Doripenem

Answer

Meropenem

Question 4

All the following statements are true regarding beta-lactams except:

Accepted Answer

Aztreonam shows cross-reactivity with cephalexin.

Answer

Methicillin is not orally bioavailable and is given parenterally.

Answer

Imipenem should be given with cilastatin

Answer

Meropenem does not require cilastatin for protection against renal toxicity.

Question 5

Burkholderia cepacia is resistant to which of the following antibiotics?

Accepted Answer

Cefotetan

Answer

Trimethoprim-sulfamethoxazole

Answer

Ceftazidime

Answer

Temocillin

Question 6

The ELISA test for virulence antigen is used to diagnose which type of Escherichia coli?

Accepted Answer

EPEC

Answer

ETEC

Answer

EIEC

Answer

EHEC

Question 7

The bacterial drug resistance in tuberculosis results from which mechanism?

Accepted Answer

Mutation

Answer

Transduction

Answer

Transformation

Answer

Plasmid mediated resistance

Question 8

How does Staphylococcus aureus become resistant to methicillin?

Accepted Answer

Transpeptidase

Answer

Heat shock protein

Answer

Protein A

Answer

Protein C

Question 9

Hain test is used for:

Accepted Answer

Detection of both rifampicin and INH resistance

Answer

Detection of INH resistance only

Answer

Detection of rifampicin resistance only

Answer

Detection of resistance to all first-line anti-tuberculosis drugs

Question 10

Which of the following drugs should not be used to treat Klebsiella infection?

Accepted Answer

Ampicillin

Answer

Amikacin

Answer

Imipenem

Answer

Tigecycline

Carbapenem-Resistant Enterobacteriaceae — MCQs

Carbapenem-Resistant Enterobacteriaceae — MCQs

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