Psychosocial Aspects of Palliative Care — MCQs
For medical termination of pregnancy, consent is given by-
The BEINGS Model of disease causation does not include which of the following factors?
A 67-year-old lady is brought in by her six children, who say that she has become senile. Six months after her husband's death, she has become more religious and spiritual, and gives a lot of money in donation. She is occupied with too many activities and sleeps less. She now believes that she has a goal to change society. She does not like being brought to the hospital and is argumentative when questioned about her actions. The diagnosis is:
All are true about dying declaration except
Dying declaration comes under?
A 65-year-old patient presents with obstructive jaundice and 15 kg weight loss. An ultrasound shows a 4 cm mass in the head of the pancreas with dilated bile ducts. Further work up includes a helical CT scan. The study shows several lesions consistent with metastasis in the right and left lobes of the liver and encasement of gastroduodenal artery. The most appropriate treatment would be:
The following procedures are recommended for palliation in a patient with obstructive jaundice due to unresectable carcinoma of head of pancreas except:
A 68-year-old man with terminal lung cancer develops confusion, myoclonus, and hallucinations after being on high-dose morphine (240 mg/day oral) for 2 weeks. His renal function shows creatinine 2.8 mg/dL. What is the most appropriate management considering the pathophysiology?
A 62-year-old woman with advanced ovarian cancer has been on oral morphine 90 mg BD for 3 months. She now reports reduced pain relief despite increasing doses, but experiences severe pain at specific sites of bone metastases. What is the best management strategy?
A 55-year-old man with terminal esophageal cancer develops respiratory secretions causing death rattle. Despite positioning and suctioning, the symptom persists. Which medication would be most appropriate and why?
Psychosocial Aspects of Palliative Care Indian Medical PG Practice Questions and MCQs
Question 1: For medical termination of pregnancy, consent is given by-
- A. Guardian
- B. Husband of the lady
- C. Concerned lady (Correct Answer)
- D. Both husband and wife
Explanation: ***Concerned lady*** - For a medical termination of pregnancy, **informed consent** must be given directly by the woman seeking the procedure. - This upholds her **autonomy** and right to make decisions regarding her own body and healthcare. *Guardian* - A guardian's consent is typically required only if the woman is a **minor** or is otherwise **legally incapacitated** and unable to provide consent herself. - In most cases, an adult woman is presumed to be competent to consent for her own medical procedures. *Husband of the lady* - The husband's consent is **not legally required** for a medical termination of pregnancy, as it is the woman's fundamental right to decide. - Requiring a husband's consent would infringe upon the woman's **bodily autonomy** and reproductive rights. *Both husband and wife* - While open communication with a spouse is often encouraged, **joint consent** from both the husband and wife is not a legal prerequisite for a medical termination of pregnancy. - The ultimate decision-making authority rests solely with the **pregnant woman**.
Question 2: The BEINGS Model of disease causation does not include which of the following factors?
- A. Spiritual factors (Correct Answer)
- B. Religious factors
- C. Social factors
- D. Nutritional factors
Explanation: ***Spiritual factors*** - The **BEINGS model** does not include \"Spiritual factors\" as one of its components. - The BEINGS acronym stands for: **B**iological, **E**nvironmental, **I**mmunological, **N**utritional, **G**enetic, and **S**ocial factors. - While spirituality can influence health outcomes, it is not a formal component of this epidemiological model. *Religious factors* - Religious factors, like spiritual factors, are also not explicitly part of the BEINGS model. - However, religious practices and beliefs may be considered as part of **social factors** (the \"S\" in BEINGS) in some contexts. - This option is less clearly excluded than spiritual factors. *Social factors* - The \"**S**\" in BEINGS specifically stands for **Social factors**, not spiritual factors. - Social factors include community networks, socioeconomic status, cultural practices, and social support systems. - These are well-established determinants of health and disease causation. *Nutritional factors* - The \"**N**\" in BEINGS stands for **Nutritional factors**. - Nutrition plays a critical role in disease causation, affecting immunity, growth, and susceptibility to various diseases. - Deficiencies or excesses in nutrition can lead to a wide range of health problems.
Question 3: A 67-year-old lady is brought in by her six children, who say that she has become senile. Six months after her husband's death, she has become more religious and spiritual, and gives a lot of money in donation. She is occupied with too many activities and sleeps less. She now believes that she has a goal to change society. She does not like being brought to the hospital and is argumentative when questioned about her actions. The diagnosis is:
- A. Depression
- B. Impulse control disorder
- C. Mania (Correct Answer)
- D. Schizophrenia
Explanation: ***Mania*** - The patient exhibits classic symptoms of **mania**: increased religiosity, excessive donations, overactivity, reduced sleep, and a **grandiose belief** ("goal to change society"). - Her **argumentativeness** and resistance to evaluation are consistent with the **lack of insight** often seen in manic episodes. *Depression* - While the death of her husband could trigger depression, her symptoms of **increased energy**, reduced sleep, and grandiosity are **contrary to typical depression** (low mood, anhedonia, fatigue). - Depression usually involves feelings of **worthlessness and guilt**, not an inflated sense of self-importance or mission. *Impulse control disorder* - This category usually involves specific problematic behaviors (e.g., gambling, kleptomania) driven by an **irresistible urge**, often preceded by tension and followed by relief. - The patient's broader constellation of symptoms, including grandiosity and reduced sleep, points to a more pervasive mood disturbance rather than a single maladaptive impulse. *Schizophrenia* - Schizophrenia is characterized by **psychosis**, including prominent hallucinations, delusions (often bizarre), disorganization in thought and speech, and negative symptoms. - While she has a **grandiose delusion**, the overall clinical picture, especially the prominent mood and energy changes, is much more indicative of a **manic episode**.
Question 4: All are true about dying declaration except
- A. Cross examination permitted (Correct Answer)
- B. Practiced in India
- C. Oath is not needed
- D. Made to Judicial Magistrate Or Medical officer
Explanation: ***Cross-examination permitted*** - A **dying declaration** is an exception to the hearsay rule, and the declarant (the dying person) is **not available for cross-examination**, as they are deceased. - The principle is based on the belief that a dying person would not lie, thus making cross-examination unnecessary for truthfulness in this context. *Practiced in India* - Dying declarations are indeed a recognized and practiced form of evidence in **Indian law**, specifically under Section 32(1) of the Indian Evidence Act, 1872. - They are considered a significant piece of evidence in criminal proceedings, especially in cases of murder or culpable homicide. *Oath is not needed* - A dying declaration does **not require an oath** to be administered to the declarant at the time of making the statement. - The belief that a person on the verge of death would speak the truth, known as the maxim **"nemo moriturus praesumitur mentiri"** (no one about to die is presumed to lie), substitutes the need for an oath. *Made to Judicial Magistrate Or Medical officer* - While a dying declaration can be made to **anyone**, including ordinary citizens, statements recorded by a **Judicial Magistrate** or a **Medical Officer** are generally given higher evidentiary value due to their impartiality and official capacity. - A medical officer can attest to the declarant's **mental fitness** at the time of making the statement, which is crucial for its admissibility.
Question 5: Dying declaration comes under?
- A. Section 60 IEA
- B. 291 CrPC
- C. Section 32 IEA (Correct Answer)
- D. Section 32 IPC
Explanation: ***Section 32 IEA*** - This section of the **Indian Evidence Act (IEA)** specifically deals with cases in which a statement of a relevant fact by a person who is dead or cannot be found, etc., is relevant. - A **dying declaration** is a statement made by a person as to the cause of their death, or as to any of the circumstances of the transaction which resulted in their death when the cause of that person's death is in question. *Section 60 IEA* - This section refers to **oral evidence** and states that oral evidence must, in all cases whatever, be direct. - It does not specifically address the admissibility of statements made by deceased persons. *291 CrPC* - This section relates to the **Code of Criminal Procedure (CrPC)** and deals with the evidence of formal character, which can be proved by affidavit. - It is not concerned with the concept of dying declarations. *Section 32 IPC* - This refers to the **Indian Penal Code (IPC)**, which defines various offenses and their punishments. - Section 32 of the IPC states that words referring to acts include illegal omissions; it does not deal with evidence or dying declarations.
Question 6: A 65-year-old patient presents with obstructive jaundice and 15 kg weight loss. An ultrasound shows a 4 cm mass in the head of the pancreas with dilated bile ducts. Further work up includes a helical CT scan. The study shows several lesions consistent with metastasis in the right and left lobes of the liver and encasement of gastroduodenal artery. The most appropriate treatment would be:
- A. Total pancreatectomy
- B. Biliary and gastric bypass
- C. Pancreaticoduodenectomy (Whipple procedure)
- D. Endoscopic stenting of bile duct (Correct Answer)
Explanation: **_Endoscopic stenting of bile duct_** - The presence of **distant liver metastases** and **vascular encasement** makes the disease inoperable and renders curative surgery impossible. - **Endoscopic stenting** offers effective palliation for **obstructive jaundice**, improving quality of life by relieving symptoms such as itching and nausea, and preventing cholangitis. *Total pancreatectomy* - This is an **extensive surgical procedure** suitable for resectable pancreatic head tumors without metastatic disease. - It is **highly morbid** and not indicated in the presence of **liver metastases** and **vascular encasement**, as it would not be curative and carries significant risks. *Biliary and gastric bypass* - This procedure aims to relieve both **biliary obstruction** and potential gastric outlet obstruction, which can occur from pancreatic head tumors. - While it addresses symptoms, it is still a **surgical intervention** with associated risks and is generally reserved for patients with a longer life expectancy or when endoscopic stenting is unsuccessful or unfeasible. It is not the most appropriate initial palliative step given the metastatic disease. *Pancreaticoduodenectomy (Whipple procedure)* - The **Whipple procedure** is the standard curative surgical treatment for **resectable pancreatic head cancers**. - However, the patient's presentation with **liver metastases** and **gastroduodenal artery encasement** indicates unresectable disease, making this procedure inappropriate and potentially harmful.
Question 7: The following procedures are recommended for palliation in a patient with obstructive jaundice due to unresectable carcinoma of head of pancreas except:
- A. Cholecystojejunostomy with jejunojejunostomy with gastrojejunostomy
- B. Hepaticojejunostomy with gastrojejunostomy
- C. Choledochoduodenostomy with gastrojejunostomy
- D. Choledochoduodenostomy, gastrojejunostomy with pancreaticojejunostomy (Correct Answer)
Explanation: ***Choledochoduodenostomy, gastrojejunostomy with pancreaticojejunostomy*** - **Pancreaticojejunostomy is NOT indicated** in palliative surgery for unresectable pancreatic cancer. - This procedure is used to anastomose the **pancreatic remnant** after **resection** (as in Whipple procedure), not in bypass operations. - Palliation focuses on **relieving biliary and gastric outlet obstruction** without performing pancreatic anastomosis, making this combination inappropriate for palliative care. *Cholecystojejunostomy with jejunojejunostomy with gastrojejunostomy* - **Cholecystojejunostomy** diverts bile flow from the gallbladder to the jejunum, relieving biliary obstruction when the cystic duct is patent. - **Gastrojejunostomy** relieves gastric outlet obstruction, a common complication of pancreatic head cancer. - This represents a valid **triple bypass** palliative approach. *Hepaticojejunostomy with gastrojejunostomy* - **Hepaticojejunostomy** creates a bypass between the common hepatic duct and the jejunum, effectively relieving biliary obstruction. - **Gastrojejunostomy** manages or prevents gastric outlet obstruction. - This **double bypass** is a standard palliative procedure for unresectable pancreatic head cancer. *Choledochoduodenostomy with gastrojejunostomy* - **Choledochoduodenostomy** directly bypasses the biliary obstruction by connecting the common bile duct to the duodenum. - **Gastrojejunostomy** addresses gastric outlet obstruction from duodenal compression by the tumor. - This **double bypass** is another widely accepted palliative approach.
Question 8: A 68-year-old man with terminal lung cancer develops confusion, myoclonus, and hallucinations after being on high-dose morphine (240 mg/day oral) for 2 weeks. His renal function shows creatinine 2.8 mg/dL. What is the most appropriate management considering the pathophysiology?
- A. Continue morphine but add naloxone infusion
- B. Add haloperidol for delirium and continue morphine
- C. Switch to fentanyl as it has no active metabolites and dose adjust for renal function (Correct Answer)
- D. Stop all opioids and use only adjuvant analgesics
Explanation: ***Switch to fentanyl as it has no active metabolites and dose adjust for renal function*** - The patient is experiencing **opioid-induced neurotoxicity (OIN)** due to the accumulation of morphine metabolites, specifically **Morphine-3-glucuronide (M3G)** and **Morphine-6-glucuronide (M6G)**, which are cleared renally. - **Fentanyl** is the preferred opioid in renal impairment because it has no clinically significant active metabolites and does not undergo significant renal excretion [1]. *Continue morphine but add naloxone infusion* - Adding **naloxone** would reverse the analgesic effects and likely precipitate an acute **withdrawal syndrome** or uncontrolled cancer pain. - This does not address the underlying cause, which is the accumulation of **neuroexcitatory metabolites** in the setting of renal failure. *Add haloperidol for delirium and continue morphine* - **Haloperidol** may mask the symptoms of delirium but does not stop the progression of **myoclonus** or neurotoxicity caused by toxic metabolites. - Continuing morphine in a patient with a **creatinine of 2.8 mg/dL** will lead to further metabolite accumulation and potential seizures. *Stop all opioids and use only adjuvant analgesics* - Abruptly stopping opioids in a patient on a high dose (240 mg/day) will lead to severe **withdrawal** and a massive **pain crisis**. - Terminal lung cancer pain requires effective opioid management; switching to a safer agent (opioid rotation) is the standard of care rather than complete discontinuation [1].
Question 9: A 62-year-old woman with advanced ovarian cancer has been on oral morphine 90 mg BD for 3 months. She now reports reduced pain relief despite increasing doses, but experiences severe pain at specific sites of bone metastases. What is the best management strategy?
- A. Add ketamine infusion for opioid resistance
- B. Switch to fentanyl patch and continue dose escalation
- C. Add gabapentin and consider palliative radiotherapy to metastatic sites (Correct Answer)
- D. Rotate to hydromorphone at equianalgesic dose
Explanation: ***Add gabapentin and consider palliative radiotherapy to metastatic sites*** - Bone metastases often cause **neuropathic pain** and inflammatory response; adding a **gabapentinoid** treats the nerve-related component that opioids may not fully cover [1]. - **Palliative radiotherapy** is highly effective for localized bone pain, often allowing for **reduced opioid requirements** and improved quality of life. *Add ketamine infusion for opioid resistance* - While **ketamine** is an NMDA antagonist used for refractory pain, it is generally reserved for specialists when common adjuncts and localized treatments fail. - It is a more invasive and complex intervention compared to **radiotherapy** and oral adjuvants like **gabapentin** for focal bone pain. *Switch to fentanyl patch and continue dose escalation* - Increasing the dose of a different opioid (dose escalation) is unlikely to resolve **opioid-insensitive** bone pain and may increase the risk of **opioid-induced hyperalgesia** [2]. - Transdermal **fentanyl** is more suitable for stable pain control and does not address the localized, metastatic nature of the patient's pain [1]. *Rotate to hydromorphone at equianalgesic dose* - **Opioid rotation** to hydromorphone is helpful if the patient is experiencing side effects, but it does not address the underlying pathology of **bone metastases** [1]. - Rotation alone does not provide the specific **neuropathic** or **anti-tumor** benefits offered by the combination of gabapentin and radiotherapy.
Question 10: A 55-year-old man with terminal esophageal cancer develops respiratory secretions causing death rattle. Despite positioning and suctioning, the symptom persists. Which medication would be most appropriate and why?
- A. Morphine - reduces respiratory drive and secretions
- B. Hyoscine butylbromide - antimuscarinic action reduces secretions without sedation (Correct Answer)
- C. Midazolam - sedates patient reducing awareness of secretions
- D. Furosemide - reduces fluid overload causing secretions
Explanation: Hyoscine butylbromide - antimuscarinic action reduces secretions without sedation - **Hyoscine butylbromide** is the preferred medication for the **death rattle** because its **antimuscarinic properties** effectively dry up salivary and bronchial secretions. - Unlike hyoscine hydrobromide, it does not cross the **blood-brain barrier**, meaning it reduces secretions with minimal risk of **sedation** or **delirium**. *Morphine - reduces respiratory drive and secretions* - While **morphine** is excellent for managing **dyspnea** and pain at the end of life, it does not possess **antisecretory** properties to manage a death rattle [1]. - Overuse of opioids for secretions can lead to unnecessary **respiratory depression** or decreased level of consciousness without fixing the noisy breathing. *Midazolam - sedates patient reducing awareness of secretions* - **Midazolam** is a benzodiazepine used for **terminal agitation** or anxiety but does not affect the production of **respiratory secretions**. - Although it might reduce patient awareness, it does not address the **audible noise** which is often distressing for the family members observing the patient [2]. *Furosemide - reduces fluid overload causing secretions* - **Furosemide** is indicated for **pulmonary edema** caused by congestive heart failure, not for the terminal accumulation of oropharyngeal secretions. - Using diuretics in a terminal patient with a death rattle is generally **ineffective** as the noise is caused by pooled saliva rather than **systemic fluid overload**.
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