Tuberculosis and Mycobacterial Diseases Practice Questions

Question 1

Phagocytosis of mycobacterium tuberculosis by macrophages is mainly mediated by:

Accepted Answer

Interferon Gamma

Answer

Interleukin 6

Answer

Interleukin 3

Answer

Interleukin 12

Question 2

XDR means extensive drug resistance to

Accepted Answer

Fluoroquinolone + at least one Group A drug (bedaquiline/linezolid)

Answer

Minimum of 1 injectable drug

Answer

H+R

Answer

1 Fluoroquinolone

Question 3

A poverty-stricken mother suffering from active tuberculosis delivers a baby. Which one of the following would be the most appropriate advice in her case?

Accepted Answer

Breast feeding and isoniazid administration

Answer

Breast feeding and BCG immunization

Answer

Expressed breast milk and BCG immunization

Answer

Stop feeds and isoniazid administration

Question 4

Mycobacterium tuberculosis having resistance to rifampicin, isoniazid, and pyrazinamide is described as -

Accepted Answer

Multi drug resistant tuberculosis

Answer

Drug resistant tuberculosis

Answer

Extremely drug resistant tuberculosis

Answer

None of the options

Question 5

Which one of the following statements is true regarding the pathogenicity of Mycobacteria species?

Accepted Answer

M. marinum is primarily associated with skin infections.

Answer

M. Africanum is typically contracted from humans or monkeys.

Answer

M. Kansasii is primarily an environmental organism that rarely causes human disease.

Answer

M. tuberculosis and M. bovis have distinct pathogenic profiles in humans.

Question 6

Most common extra pulmonary involvement of TB ?

Accepted Answer

Lymph nodes

Answer

Bone

Answer

Ileocecal

Answer

Pleura

Question 7

A 45-year-old HIV-positive man presents with fever and cough. Sputum culture shows acid-fast bacilli. Which of the following drugs is essential in the treatment regimen?

Accepted Answer

Isoniazid

Answer

Doxycycline

Answer

Amoxicillin

Answer

Ciprofloxacin

Question 8

What should you do next for a 35-year-old man who is positive for HBsAg and HBeAg, discovered incidentally during blood donation screening, with normal SGOT and SGPT laboratory values?

Accepted Answer

HBV-DNA estimation

Answer

Observation

Answer

Liver biopsy

Answer

Interferon therapy

Question 9

Devi, a 28 year female, has diarrhea, confusion, high grade fever with bilateral pneumonitis. The diagnosis is -

Accepted Answer

Legionella

Answer

H. influenzae

Answer

Streptococcus pneumoniae

Answer

Neisseria meningitidis

Question 10

All the following are causes of a painful limp, except which of the following?

Accepted Answer

Infantile Coxa Vara (Coxa Vara)

Answer

Slipped femoral epiphysis (SCFE)

Answer

Tuberculosis (TB) of the hip

Answer

Perthes disease (Legg-Calvé-Perthes disease)

Tuberculosis and Mycobacterial Diseases — MCQs

Tuberculosis and Mycobacterial Diseases — MCQs

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