Relapsing Polychondritis — MCQs

A 12 year old girl was brought with fever, malaise, and migrating polyarthritis. She had a history of recurrent throat infections in the past. Elevated erythrocyte sedimentation rate is noted. Which among the following is NOT a major Jones criteria for diagnosis of acute rheumatic fever?

Osteoarthritis is associated with all of the following except -

A child presents with high grade fever, inspiratory stridor and develops swallowing difficulty with drooling of saliva since last 4-6 hours. Which of the following treatment is recommended apart from general airway management?

Which of the following conditions is least likely to present with polyarticular involvement in clinical practice?

A 28-year-old female presents with a 3-month history of violaceous, flat-topped papules on her wrists and lower back associated with intense pruritus. Examination reveals white lacy streaks on the buccal mucosa bilaterally. She was recently started on antihypertensive medication 4 months ago. Histopathology shows hyperkeratosis, irregular acanthosis, and band-like lymphocytic infiltrate at the dermoepidermal junction. What is the most appropriate next step in management?

A study of persons developing skin lesions following sun exposure is conducted. The lesions are not found on skin protected from ultraviolet light. Biopsies of involved skin show immunoglobulin G deposition along the dermal-epidermal junction, along with vacuolization of the basal layer and a perivascular lymphocytic infiltrate. No other organ involvement is present. Which of the following diseases do these patients most likely have?

Gottron's papules are a characteristic clinical finding in which of the following conditions?

Salt and pepper dyschromatosis is seen in which of the following conditions?

Which of the following drugs is not associated with drug-induced pemphigus?

A 25-year-old man complains of eruptions of blisters on his scalp, inner surface of the groin, and in his mouth. The blisters rupture easily and leave large crusted areas. Histologically, the lesions show separation of the stratum spinosum from the basal layer. The results of direct immunofluorescence microscopy for IgG are shown. Which of the following proteins is targeted by IgG autoantibody in the skin of this patient?