Blood Glucose Regulation Practice Questions

Question 1

Which of the following statements correctly describes the effect of insulin and glucagon on gluconeogenesis?

Accepted Answer

Glucagon decreases fructose 2,6-bisphosphate levels, stimulating gluconeogenesis.

Answer

Insulin increases the levels of fructose 2,6-bisphosphate, which inhibits gluconeogenesis.

Answer

Insulin acts through a kinase to promote glycolysis.

Answer

Fructose 2,6-bisphosphate is an activator of glycolysis.

Question 2

A patient had dinner at 8 PM at night and does his blood sugar test at 7 AM in the morning. What is the major source of glucose at this time?

Accepted Answer

Liver Glycogen

Answer

Muscle Glycogen

Answer

Gluconeogenesis

Answer

Dietary Carbohydrate

Answer

Ketone bodies

Question 3

Which of the following statements best describes the mechanism of action of insulin on target cells?

Accepted Answer

Insulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

Answer

Insulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

Answer

Insulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

Answer

Insulin enters the cell and causes the release of calcium ions from intracellular stores.

Question 4

An 8-month-old infant is brought in with poor feeding, lethargy, hypotonia, and hepatomegaly. Labs reveal hypoglycemia and metabolic acidosis. Which condition is most likely?

Accepted Answer

Von Gierke disease

Answer

Hereditary fructose intolerance

Answer

Galactosemia

Answer

Pompe disease

Answer

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency

Question 5

Which hormone is NOT increased in stress?

Accepted Answer

Insulin

Answer

Glucagon

Answer

Cortisol

Answer

Epinephrine

Question 6

Final common pathway of metabolism of carbohydrate, lipids, and protein metabolism is?

Accepted Answer

TCA

Answer

Gluconeogenesis

Answer

HMP pathway

Answer

Glycolysis

Question 7

All of the following are increased in Acute stress except

Accepted Answer

Insulin

Answer

Growth hormone

Answer

Epinephrine

Answer

Glucagon

Question 8

Which of the following statements about insulin-mediated transport of glucose is correct?

Accepted Answer

Seen in adipose tissue

Answer

Via GLUT-2

Answer

Main mechanism in RBCs

Answer

Occurs primarily in the brain

Question 9

Which one of the following statements concerning gluconeogenesis is correct?

Accepted Answer

It is important in maintaining blood glucose during the normal overnight fast.

Answer

It occurs primarily in the liver.

Answer

It is stimulated by elevated levels of acetyl CoA.

Answer

It is primarily inhibited by insulin.

Question 10

Glucose can be synthesized from all except

Accepted Answer

Acetoacetate

Answer

Amino acids

Answer

Lactic acid

Answer

Glycerol

Blood Glucose Regulation — MCQs

Blood Glucose Regulation — MCQs

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