Lymphatic Drainage — MCQs
Which levels of cervical lymph nodes are included in a modified radical neck dissection?
Which lymph nodes are involved in the lymphatic drainage of the lateral wall of the nose?
Lymph node metastasis in neck is almost never seen with:
A patient with head and neck cancer has a contralateral lymph node of 3 cm size. What is the N staging?
Which lymph nodes drain the skin and fascia of the great toe?
Lympho-venous anastomosis is done for
The thoracic duct crosses from the right to the left at the level of
Which of the following cancers do not present with cervical lymph node involvement?
Lymph vessels which drain the posterior 1/3rd of the tongue:
Biopsy of the exposed surface of the palatine tonsil reveals which type of tissue?
Lymphatic Drainage Indian Medical PG Practice Questions and MCQs
Question 1: Which levels of cervical lymph nodes are included in a modified radical neck dissection?
- A. I-IV
- B. I-V (Correct Answer)
- C. I-III
- D. II-VI
Explanation: ***I-V*** - A modified radical neck dissection typically removes lymph nodes from levels **I through V**, along with preservation of one or more non-lymphatic structures (sternocleidomastoid muscle, internal jugular vein, or spinal accessory nerve). - This extensive dissection addresses potential metastasis to these node groups from head and neck cancers, crucial for adequate oncologic clearance while aiming for functional preservation. *I-III* - This limited dissection would likely be insufficient for many head and neck cancers, as spread often extends beyond level III. - It would miss potential metastases in the lower jugular and posterior triangle nodes, increasing the risk of recurrence. *I-IV* - This dissection omits **level V**, which includes the posterior triangle nodes, a common site for metastatic spread, especially for cancers of the oropharynx, hypopharynx, and thyroid. - Excluding level V would be considered an incomplete radical or modified radical neck dissection in many clinical scenarios. *II-VI* - This option incorrectly excludes lymph nodes at **level I** (submental and submandibular nodes), which are critical draining sites for many oral cavity cancers. - Including level VI (anterior compartment nodes) is typically part of a central compartment neck dissection, often performed for thyroid cancer, but is usually not part of a standard modified radical neck dissection for other head and neck primaries unless specifically indicated.
Question 2: Which lymph nodes are involved in the lymphatic drainage of the lateral wall of the nose?
- A. Deep cervical nodes
- B. Retropharyngeal nodes
- C. Submandibular nodes
- D. All of the options (Correct Answer)
Explanation: ***All of the options*** - The lymphatic drainage from the **lateral wall of the nose** follows a sequential pathway involving **submandibular nodes**, **retropharyngeal nodes**, and ultimately the **deep cervical nodes**. - This question tests understanding of the complete lymphatic drainage pathway, not just the primary drainage site. - All three node groups are anatomically involved in draining lymph from the lateral nasal wall. **Drainage Pathway:** - **Submandibular nodes** (Primary): The anterior and middle portions of the lateral nasal wall drain primarily to the submandibular lymph nodes. - **Retropharyngeal nodes** (Secondary): The posterior portions of the lateral wall and areas near the nasal pharynx drain to retropharyngeal nodes. - **Deep cervical nodes** (Final pathway): Lymph from both submandibular and retropharyngeal nodes eventually drains into the deep cervical chain, particularly the jugulodigastric and juguloomohyoid nodes. *Why not just one node group?* - The lateral wall of the nose has an extensive lymphatic network with multiple drainage routes. - Different regions of the lateral wall have preferential drainage to different node groups. - Understanding the complete drainage pathway is clinically important for assessing spread of infections and malignancies from the nasal cavity.
Question 3: Lymph node metastasis in neck is almost never seen with:
- A. Carcinoma vocal cords (Correct Answer)
- B. Supraglottic carcinoma
- C. Carcinoma of tonsil
- D. Papillary carcinoma thyroid
Explanation: ***Carcinoma vocal cords*** - The **vocal cords** are relatively poor in lymphatic drainage, which significantly reduces the likelihood of regional lymph node metastasis. - Due to this sparse lymphatic network, spread to cervical lymph nodes is rare, especially in early-stage disease. *Supraglottic carcinoma* - **Supraglottic** regions have a rich lymphatic network, leading to a high incidence of cervical lymph node metastasis, even in early stages. - Bilateral lymphatic drainage further increases the risk of nodal involvement. *Carcinoma of tonsil* - The **tonsils** are richly supplied with lymphatic vessels, making them prone to early and frequent metastasis to cervical lymph nodes. - Metastasis is often seen in levels II, III, and IV of the neck. *Papillary carcinoma thyroid* - **Papillary thyroid carcinoma** commonly metastasizes to regional lymph nodes, with documented rates as high as 30-80%. - Nodal metastasis can occur in the central compartment (level VI) and lateral neck (levels II-V).
Question 4: A patient with head and neck cancer has a contralateral lymph node of 3 cm size. What is the N staging?
- A. N2a Single Ipsilateral 3 to 6 cm
- B. N1 Single Ipsilateral Equal to or <3 cm
- C. N3 Single or Multiple Ipsilateral, Bilateral or Contralateral Any node >6 cm
- D. N2c Single or Multiple Bilateral or Contralateral None > 6 cm (Correct Answer)
Explanation: ***N2c (Single or Multiple, Bilateral or Contralateral, None > 6 cm)*** - A 3 cm **contralateral** lymph node falls under the **N2c** category according to the AJCC staging system for head and neck cancers. - **N2c** indicates involvement of **contralateral** or **bilateral lymph nodes**, with the largest node being **no greater than 6 cm**. - This is the correct staging for the described clinical scenario. *N2a (Single, Ipsilateral, 3 to 6 cm)* - This option incorrectly describes an **ipsilateral** lymph node, whereas the question specifies a **contralateral** node. - **N2a** is defined by a single **ipsilateral** lymph node between **3 and 6 cm** in greatest dimension. - The key differentiator is **laterality** (ipsilateral vs contralateral). *N1 (Single, Ipsilateral, Equal to or <3 cm)* - This option refers to an **ipsilateral** lymph node that is **3 cm or smaller**, which does not match the contralateral location provided in the question. - **N1** describes a single **ipsilateral** lymph node that is **≤ 3 cm** in greatest dimension. - This fails on both **laterality** (ipsilateral vs contralateral) and **size criteria** (the node is exactly 3 cm, at the boundary). *N3 (Single or Multiple, Ipsilateral/Bilateral/Contralateral, Any node >6 cm)* - While it includes contralateral involvement, **N3** is specifically for a lymph node **greater than 6 cm**, which is not the case for a 3 cm node. - A **N3** classification applies when **any** regional lymph node (ipsilateral, bilateral, or contralateral) exceeds **6 cm** in greatest dimension. - The described 3 cm node does not meet the **size threshold** for N3 staging.
Question 5: Which lymph nodes drain the skin and fascia of the great toe?
- A. Superficial inguinal lymph nodes (Correct Answer)
- B. External iliac lymph nodes
- C. Internal iliac lymph nodes
- D. Deep inguinal lymph nodes
Explanation: ***Superficial inguinal lymph nodes*** - The **superficial inguinal lymph nodes** are responsible for draining lymph from the skin and fascia of the lower limb, including the **great toe**. [1] - They are located in the superficial fascia below the inguinal ligament and receive lymphatic vessels associated with the **great saphenous vein**. *External iliac lymph nodes* - The external iliac lymph nodes drain structures within the **pelvis** and receive lymph from the **deep inguinal lymph nodes**, not directly from the skin of the great toe. - They are located along the external iliac artery and vein. *Internal iliac lymph nodes* - The internal iliac lymph nodes primarily drain lymph from the **pelvic organs** and the **perineum**. - They do not directly receive lymphatic drainage from the great toe or the superficial lower limb. *Deep inguinal lymph nodes* - The deep inguinal lymph nodes are located deeper, medial to the **femoral vein**, and receive lymph mainly from the deep structures of the lower limb. - While they eventually drain into the external iliac nodes, they do not directly drain the superficial skin and fascia of the great toe.
Question 6: Lympho-venous anastomosis is done for
- A. Cystic hygroma
- B. Malignant lymphoedema
- C. Lymphoid cyst
- D. Filarial lymphoedema (Correct Answer)
Explanation: ***Filarial lymphoedema*** - **Lympho-venous anastomosis (LVA)** is a microsurgical technique used to bypass damaged lymphatic vessels and directly connect lymphatic channels to small veins. This procedure is primarily effective in treating **lymphedema due to lymphatic obstruction**, such as that caused by filarial infection. - In **filarial lymphoedema**, the lymphatic obstruction leads to accumulation of lymph fluid. LVA helps to restore lymphatic drainage, reducing limb swelling and improving symptoms, particularly in the early stages of the disease. *Cystic hygroma* - A **cystic hygroma** is a congenital lymphatic malformation, typically treated by surgical excision, sclerotherapy, or laser ablation. - It involves abnormally dilated lymphatic spaces and doesn't usually benefit from LVA, as the primary issue is malformation rather than obstruction requiring a bypass. *Malignant lymphoedema* - **Malignant lymphoedema** (secondary to cancer or its treatment) is often complicated by active tumor burden, radiation fibrosis, or extensive nodal involvement. - While LVA might be considered in carefully selected cases, its efficacy can be limited due to underlying cancer and the diffuse nature of the lymphatic damage, making it a less common primary indication compared to filarial lymphedema. *Lymphoid cyst* - A **lymphoid cyst** is a localized collection of lymph, often treated by aspiration, sclerotherapy, or surgical excision. - It is not a widespread lymphatic drainage disorder that would necessitate a bypass procedure like lympho-venous anastomosis.
Question 7: The thoracic duct crosses from the right to the left at the level of
- A. T12 vertebra
- B. T2 vertebra
- C. T4-T5 vertebra (Correct Answer)
- D. T6 vertebra
Explanation: ***T4-T5 vertebra*** - The **thoracic duct** crosses from the right to the left side of the vertebral column at the level of the **T4-T5 vertebrae**, specifically just above the root of the left lung. - This crossover is an important anatomical landmark as it signifies the duct's ascent towards the neck to drain into the left subclavian vein. *T12 vertebra* - The **thoracic duct** originates from the **cisterna chyli** at the level of the L1 or L2 vertebra and ascends into the thorax at or below the T12 vertebra, it does not cross over at this level. - This level primarily marks its entry into the thoracic cavity, not its main crossover point. *T6 vertebra* - While the **thoracic duct** is present in the thorax at this level, it does not undergo its characteristic crossover from right to left at the T6 vertebra. - The duct continues its ascent along the right side of the vertebral column before moving across. *T2 vertebra* - By the level of the T2 vertebra, the **thoracic duct** has already crossed to the left side of the vertebral column and is ascending towards its termination in the neck. - The crossover event occurs more inferiorly, at the T4-T5 level.
Question 8: Which of the following cancers do not present with cervical lymph node involvement?
- A. Papillary thyroid cancer
- B. Oral cancer
- C. Glottic Cancer (Correct Answer)
- D. Subglottic Cancer
Explanation: ***Glottic Cancer*** - **Glottic cancers** rarely present with cervical lymph node involvement because the **vocal cords** have a sparse lymphatic drainage system. - This anatomical feature limits the early spread of cancer cells to regional lymph nodes, distinguishing it from other head and neck cancers. *Subglottic Cancer* - **Subglottic cancers** frequently metastasize to cervical lymph nodes, specifically the **paratracheal** and **prelaryngeal nodes**, due to a richer lymphatic network. - The disease often presents at a more advanced stage because symptoms may be subtle until significant tumor burden or nodal involvement occurs. *Papillary thyroid cancer* - **Papillary thyroid cancer** commonly metastasizes to the cervical lymph nodes, often presenting with palpable **lymphadenopathy** even with small primary tumors. - Lymphatic spread is a hallmark feature, and **central neck dissection** is frequently performed as part of the surgical treatment. *Oral cancer* - **Oral cancers** (e.g., squamous cell carcinoma of the tongue, buccal mucosa) have a high propensity for early metastasis to **cervical lymph nodes**. - The rich lymphatic drainage of the oral cavity means that cervical lymph node involvement is a significant prognostic factor and is routinely assessed during staging.
Question 9: Lymph vessels which drain the posterior 1/3rd of the tongue:
- A. Submental node
- B. Submandibular node
- C. Preauricular node
- D. Jugulodigastric node (Correct Answer)
Explanation: ***Jugulodigastric node*** - The **jugulodigastric node** (also known as the principal node of Küttner) is a prominent deep cervical lymph node that drains lymphatic fluid directly from the **posterior 1/3rd of the tongue**. - Its strategic location at the junction of the internal jugular vein and the posterior belly of the digastric muscle makes it a primary drainage site for malignant lesions of the posterior tongue. *Submental node* - The **submental nodes** primarily drain the central part of the lower lip, the floor of the mouth, and the tip of the tongue. - They do not receive lymphatic drainage from the posterior third of the tongue. *Submandibular node* - The **submandibular nodes** drain most of the anterior two-thirds of the tongue, excluding the tip, as well as the oral cavity structures like the floor of the mouth and gingivae. - They are not the primary drainage site for the posterior third of the tongue. *Preauricular node* - **Preauricular nodes** (also known as parotid lymph nodes) are located in front of the ear and drain the temporal region, outer ear, and eyelids. - They have no direct lymphatic drainage connection to any part of the tongue.
Question 10: Biopsy of the exposed surface of the palatine tonsil reveals which type of tissue?
- A. Stratified squamous epithelium (Correct Answer)
- B. Simple squamous epithelium
- C. Simple columnar epithelium
- D. Pseudostratified columnar ciliated epithelium
Explanation: The palatine tonsils are part of the **oropharynx**, which is subjected to mechanical abrasion from food and drink. **Stratified squamous epithelium** provides robust protection against such friction and is characteristic of surfaces needing high wear resistance. *Simple squamous epithelium* - This type of epithelium is found in areas where **diffusion** or **filtration** is important, such as the lining of blood vessels (endothelium) and alveoli of the lungs. - It would not provide adequate protection for the exposed surface of the tonsil that is subject to frequent mechanical stress. *Simple columnar epithelium* - Characterized by cells taller than they are wide, often found in the **gastrointestinal tract** for absorption and secretion. - It lacks the multi-layered structure needed for protection against the abrasive forces typical in the oropharynx. *Pseudostratified columnar ciliated epithelium* - This epithelium is primarily found in the **respiratory tract**, where its cilia help move mucus and trapped particles. - While it offers some protection, its primary function is not mechanical resistance, and it is not found on the exposed surfaces of the palatine tonsils.
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