Question 21: Which one of the following is the commonest extra-salivary gland manifestation of mumps in adults?
- A. Orchitis (Correct Answer)
- B. Pancreatitis
- C. Polyarthritis
- D. Hydrocephalus
Explanation: **Orchitis**
- **Orchitis**, the inflammation of the testes, is the most common extra-salivary gland manifestation of mumps in **post-pubertal males** and can lead to **testicular atrophy** and infertility.
- The incidence of orchitis in adult males with mumps can be as high as 30–50%.
*Pancreatitis*
- While mumps can cause **pancreatitis**, it is less common than orchitis, occurring in only about 2-5% of cases [1].
- Mumps-induced pancreatitis is usually mild and self-limiting [1].
*Polyarthritis*
- **Polyarthritis** is a rare complication of mumps, typically resolving without long-term sequelae.
- It is much less frequently observed compared to orchitis, especially in adults.
*Hydrocephalus*
- **Hydrocephalus** is an extremely rare and severe complication of mumps, often associated with mumps **meningoencephalitis**.
- This complication involves an abnormal accumulation of cerebrospinal fluid, which is highly uncommon following mumps infection.