UPSC-CMS 2017 — Dermatology

Q: All of the following statements are true for keloids EXCEPT:

True keloid does not spread into surrounding tissue. ***True keloid does not spread into surrounding tissue*** - This statement is **incorrect** as a defining characteristic of keloids is their tendency to **spread beyond the original wound boundaries**, invading surrounding healthy tissue. - This expansive growth differentiates keloids from hypertrophic scars, which remain confined to the site of injury. *The maturation and stabilization of the collagen fibrils is inhibited* - This statement is **true**. In keloids, there is an impairment in the normal maturation process of collagen, leading to an accumulation of **immature, disorganized collagen fibrils**. - This abnormal collagen synthesis and degradation contribute to the excessive and persistent fibrosis characteristic of keloids. *It is rarely seen in white skinned persons and is more common over the sternum* - This statement is **true**. Keloids are more prevalent in individuals with **skin of color (e.g., African, Hispanic, and Asian descent)** and are less common in Caucasians. - Common locations for keloids include the **sternum**, earlobes, shoulders, and upper back, areas under significant skin tension. *True keloid continues to become worse even after one year* - This statement is **true**. Unlike hypertrophic scars which may regress over time, keloids tend to be **persistent and progressive**, often continuing to grow and worsen in size and appearance even years after the initial injury. - They typically do not resolve spontaneously and may even recur after excision. [Practice more Dermatology PYQs on OnCourse]

Q: Painless genital ulcer is found in which one of the following genital infections?

Granuloma inguinale. ***Granuloma inguinale*** - Presents as a **painless, slowly progressive ulcerative lesion** that bleeds easily. - Caused by *Klebsiella granulomatis*, it starts as a papule and then becomes a **beefy red, granulation tissue-like ulcer**. *Lymphogranuloma venerum* - Initially presents with a **small, painless papule or vesicle** that often goes unnoticed. - The most prominent clinical feature is **regional lymphadenopathy (buboes)**, which can be painful and suppurate. *Chancroid* - Characterized by **painful, deep, irregular ulcers** with ragged undermined borders. - These ulcers are typically **soft** and can be accompanied by painful inguinal lymphadenopathy. *Herpes simplex* - Causes **multiple, painful vesicular lesions** that quickly erode into ulcers. - These lesions often recur and are associated with **burning or itching sensations** before eruption. [Practice more Dermatology PYQs on OnCourse]

2 Previous Year Questions with Answers & Explanations

Questions

All Subjects Anatomy (4)Anesthesiology (1)Biochemistry (1)Community Medicine (36)Dermatology (2)Internal Medicine (8)Microbiology (2)Obstetrics and Gynecology (26)Ophthalmology (2)Pathology (4)Pediatrics (1)Pharmacology (3)Physiology (2)Surgery (23)

All of the following statements are true for keloids EXCEPT:

Painless genital ulcer is found in which one of the following genital infections?

UPSC-CMS 2017 - Dermatology UPSC-CMS Practice Questions and MCQs

Question 1: All of the following statements are true for keloids EXCEPT:

A. The maturation and stabilization of the collagen fibrils is inhibited
B. It is rarely seen in white skinned persons and is more common over the sternum
C. True keloid does not spread into surrounding tissue (Correct Answer)
D. True keloid continues to become worse even after one year

Explanation: ***True keloid does not spread into surrounding tissue*** - This statement is **incorrect** as a defining characteristic of keloids is their tendency to **spread beyond the original wound boundaries**, invading surrounding healthy tissue. - This expansive growth differentiates keloids from hypertrophic scars, which remain confined to the site of injury. *The maturation and stabilization of the collagen fibrils is inhibited* - This statement is **true**. In keloids, there is an impairment in the normal maturation process of collagen, leading to an accumulation of **immature, disorganized collagen fibrils**. - This abnormal collagen synthesis and degradation contribute to the excessive and persistent fibrosis characteristic of keloids. *It is rarely seen in white skinned persons and is more common over the sternum* - This statement is **true**. Keloids are more prevalent in individuals with **skin of color (e.g., African, Hispanic, and Asian descent)** and are less common in Caucasians. - Common locations for keloids include the **sternum**, earlobes, shoulders, and upper back, areas under significant skin tension. *True keloid continues to become worse even after one year* - This statement is **true**. Unlike hypertrophic scars which may regress over time, keloids tend to be **persistent and progressive**, often continuing to grow and worsen in size and appearance even years after the initial injury. - They typically do not resolve spontaneously and may even recur after excision.

Question 2: Painless genital ulcer is found in which one of the following genital infections?

A. Lymphogranuloma venerum
B. Granuloma inguinale (Correct Answer)
C. Chancroid
D. Herpes simplex

Explanation: ***Granuloma inguinale*** - Presents as a **painless, slowly progressive ulcerative lesion** that bleeds easily. - Caused by *Klebsiella granulomatis*, it starts as a papule and then becomes a **beefy red, granulation tissue-like ulcer**. *Lymphogranuloma venerum* - Initially presents with a **small, painless papule or vesicle** that often goes unnoticed. - The most prominent clinical feature is **regional lymphadenopathy (buboes)**, which can be painful and suppurate. *Chancroid* - Characterized by **painful, deep, irregular ulcers** with ragged undermined borders. - These ulcers are typically **soft** and can be accompanied by painful inguinal lymphadenopathy. *Herpes simplex* - Causes **multiple, painful vesicular lesions** that quickly erode into ulcers. - These lesions often recur and are associated with **burning or itching sensations** before eruption.