Question 1: Consider the following statements regarding folic acid:
1. It is needed for normal development of blood cells in the marrow
2. It has a role in synthesis of nucleic acids
3. It is resistant to boiling Which of the above statements is/are correct?
- A. 1 and 2 (Correct Answer)
- B. 1 and 3
- C. 1 only
- D. 2 and 3
Explanation: ***1 and 2***
- **Folic acid** is a crucial coenzyme required for the synthesis of **purines** and **pyrimidines**, which are essential components of **DNA** and **RNA**.
- This role in nucleic acid synthesis is vital for cell division and growth, explaining its necessity for the normal development of **blood cells** in the **bone marrow**.
*1 and 3*
- While folic acid is needed for normal blood cell development, it is generally **not resistant to boiling**.
- Folic acid is quite **heat-sensitive** and its content can significantly decrease with cooking, especially prolonged boiling.
*1 only*
- Folic acid's role extends beyond just blood cell development; its involvement in nucleic acid synthesis is a fundamental biochemical function.
- The synthesis of **DNA** and **RNA** is a primary reason why it's essential for rapidly dividing cells, like those in the bone marrow.
*2 and 3*
- Although folic acid plays a critical role in the synthesis of nucleic acids, it is **not resistant to boiling**.
- Its heat-sensitive nature means that cooking methods can significantly impact the availability of **folic acid** in foods.