NEET-PG 2022 — Dental

Q: Uncontrolled diabetes poses a problem to a prosthodontist as

more bone resorption. ***more bone resorption*** - Uncontrolled diabetes *impairs bone metabolism and regeneration*, leading to increased **osteoclastic activity** and reduced osteoblastic function, which results in *greater bone loss*. - This heightened bone resorption makes it difficult to achieve **stable denture retention** and can compromise the success of *dental implants* and other prosthodontic treatments. *increased salivary flow* - Diabetes often causes **xerostomia** (dry mouth) due to *reduced salivary gland function*, not increased salivary flow. - Reduced salivary flow impacts *denture retention, lubrication, and oral hygiene*, making it a further challenge for prosthodontists. *less bone resorption* - This statement is incorrect; uncontrolled diabetes is associated with *increased, not decreased, bone resorption*. - **Hyperglycemia** negatively affects bone health through various mechanisms, including advanced glycation end-products (AGEs) formation and systemic inflammation. *increased tissue laxity* - While diabetes can affect connective tissues, the primary and most significant prosthodontic concern regarding bone is **increased bone resorption**, not necessarily generalized tissue laxity that directly impacts denture stability in the same way. - **Poorly controlled diabetes** can lead to issues like reduced wound healing and increased susceptibility to infection, which are also relevant, but bone resorption is a more direct mechanical issue for prosthodontics. [Practice more Dental PYQs on OnCourse]

Q: All are true regarding oral hairy leukoplakia except which of the following?

It is premalignant. ***It is premalignant*** - Oral hairy leukoplakia is associated with **Epstein-Barr virus (EBV)** and is not considered a precancerous condition [1]. - This condition is primarily seen in immunocompromised individuals and does not progress to malignancy [1]. *Hyperkeratosis on HPE* - Histopathological examination typically reveals **keratinized epithelial layers** but is not characterized by prominent hyperkeratosis. - Rather, it shows **ballooning degeneration** of epithelial cells rather than classic hyperkeratotic features [1]. *Associated with EBV infection* - Oral hairy leukoplakia is strongly associated with **EBV**, particularly in immunocompromised patients [1]. - It manifests as white plaques on the lateral borders of the tongue due to **viral replication** of EBV-infected epithelial cells [1]. *Seen in HIV infected patients* - This condition is commonly seen in **HIV-infected individuals**, particularly those with a low CD4 count [1]. - It serves as a clinical marker for **immunosuppression** but is not exclusive to HIV [1]. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Lung, pp. 737-738. [Practice more Dental PYQs on OnCourse]

2 Previous Year Questions with Answers & Explanations

Questions

Uncontrolled diabetes poses a problem to a prosthodontist as

All are true regarding oral hairy leukoplakia except which of the following?

NEET-PG 2022 - Dental NEET-PG Practice Questions and MCQs

Question 1: Uncontrolled diabetes poses a problem to a prosthodontist as

A. more bone resorption (Correct Answer)
B. increased salivary flow
C. less bone resorption
D. increased tissue laxity

Explanation: ***more bone resorption*** - Uncontrolled diabetes *impairs bone metabolism and regeneration*, leading to increased **osteoclastic activity** and reduced osteoblastic function, which results in *greater bone loss*. - This heightened bone resorption makes it difficult to achieve **stable denture retention** and can compromise the success of *dental implants* and other prosthodontic treatments. *increased salivary flow* - Diabetes often causes **xerostomia** (dry mouth) due to *reduced salivary gland function*, not increased salivary flow. - Reduced salivary flow impacts *denture retention, lubrication, and oral hygiene*, making it a further challenge for prosthodontists. *less bone resorption* - This statement is incorrect; uncontrolled diabetes is associated with *increased, not decreased, bone resorption*. - **Hyperglycemia** negatively affects bone health through various mechanisms, including advanced glycation end-products (AGEs) formation and systemic inflammation. *increased tissue laxity* - While diabetes can affect connective tissues, the primary and most significant prosthodontic concern regarding bone is **increased bone resorption**, not necessarily generalized tissue laxity that directly impacts denture stability in the same way. - **Poorly controlled diabetes** can lead to issues like reduced wound healing and increased susceptibility to infection, which are also relevant, but bone resorption is a more direct mechanical issue for prosthodontics.

Question 2: All are true regarding oral hairy leukoplakia except which of the following?

A. It is a benign condition associated with EBV infection.
B. Presents with corrugated white plaques
C. It is premalignant (Correct Answer)
D. Hyperkeratosis on HPE is not typically seen.

Explanation: ***It is premalignant*** - Oral hairy leukoplakia is associated with **Epstein-Barr virus (EBV)** and is not considered a precancerous condition [1]. - This condition is primarily seen in immunocompromised individuals and does not progress to malignancy [1]. *Hyperkeratosis on HPE* - Histopathological examination typically reveals **keratinized epithelial layers** but is not characterized by prominent hyperkeratosis. - Rather, it shows **ballooning degeneration** of epithelial cells rather than classic hyperkeratotic features [1]. *Associated with EBV infection* - Oral hairy leukoplakia is strongly associated with **EBV**, particularly in immunocompromised patients [1]. - It manifests as white plaques on the lateral borders of the tongue due to **viral replication** of EBV-infected epithelial cells [1]. *Seen in HIV infected patients* - This condition is commonly seen in **HIV-infected individuals**, particularly those with a low CD4 count [1]. - It serves as a clinical marker for **immunosuppression** but is not exclusive to HIV [1]. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Lung, pp. 737-738.