Which tract is responsible for the ventral tegmental decussation in the cerebral peduncle?
Lining epithelium of vagina is
Oxyntic cells are present in -
Which is the first bone to start ossifying?
The incudomalleolar joint is a?
Hilton's law primarily relates to which of the following?
Fossa ovalis is a remnant of -
Nephron is derived from ?
Fibrous stroma of liver is derived from -
What structures are derived from the neural crest?
NEET-PG 2015 - Anatomy NEET-PG Practice Questions and MCQs
Question 51: Which tract is responsible for the ventral tegmental decussation in the cerebral peduncle?
- A. Tectospinal tract
- B. Vestibulospinal tract
- C. Rubrospinal tract (Correct Answer)
- D. Tectobulbar tract
Explanation: The rubrospinal tract originates in the red nucleus and decussates in the ventral tegmental decussation at the level of the midbrain, before descending to the spinal cord. This decussation is the characteristic feature that distinguishes it from other descending tracts. It primarily modulates flexor muscle tone and fine motor control of distal limb muscles. The tectospinal tract originates in the superior colliculus and decussates immediately as the dorsal tegmental decussation, involved in coordinating head and eye movements in response to stimuli. The vestibulospinal tract originates in the vestibular nuclei and descends ipsilaterally and contralaterally [1], but it does not form a distinct ventral tegmental decussation in the cerebral peduncle. It is crucial for maintaining posture and balance by influencing extensor muscles [1]. The tectobulbar tract arises from the superior colliculus and projects to cranial nerve nuclei, but it does not undergo the specific ventral tegmental decussation.
Question 52: Lining epithelium of vagina is
- A. Squamous epithelium (Correct Answer)
- B. Columnar epithelium
- C. Transitional epithelium
- D. Secretory epithelium
Explanation: Squamous epithelium * The vagina is lined by stratified squamous non-keratinized epithelium [1], providing a protective barrier against friction and pathogens. * This type of epithelium is well-suited for areas subject to significant mechanical stress, such as during intercourse and childbirth. Columnar epithelium * Columnar epithelium [2] is typically found in areas specialized for secretion and absorption, such as the gastrointestinal tract and glandular linings. * It would not offer the necessary protective qualities for the vaginal environment. Transitional epithelium * Transitional epithelium is a specialized stratified epithelium found in the urinary tract, capable of stretching and distending. * It is not found in the vagina, which requires a more robust, friction-resistant lining. Secretory epithelium * While the cervix has secretory glands, the lining of the vagina itself is not primarily secretory. * The primary role of the vaginal lining is protection, not secretion, and its cells do not typically produce a large amount of substances.
Question 53: Oxyntic cells are present in -
- A. Pylorus
- B. Cardia
- C. Body (Correct Answer)
- D. None of the options
Explanation: ***Body*** - **Oxyntic cells**, also known as **parietal cells**, are predominantly located in the **fundus and body** of the stomach [1], [2]. - These cells are responsible for secreting **hydrochloric acid (HCl)** and **intrinsic factor**, which are crucial for digestion and vitamin B12 absorption [1]. - The gastric glands in the body contain the highest concentration of parietal cells [2]. *Pylorus* - The pylorus is the distal part of the stomach that connects to the duodenum. - It primarily contains **G cells**, which secrete **gastrin**, a hormone that stimulates HCl secretion from parietal cells [3]. - Pyloric glands contain mainly mucus-secreting cells, with few or no parietal cells [2]. *Cardia* - The cardia is the region near the gastroesophageal junction (entrance of the stomach). - This area primarily contains **cardiac glands** with mucus-secreting cells that protect the esophageal lining from gastric acid reflux. - Parietal cells are sparse or absent in the cardia [2]. *None of the options* - This option is incorrect because the **body of the stomach** is the correct location for oxyntic cells.
Question 54: Which is the first bone to start ossifying?
- A. Femur
- B. Clavicle (Correct Answer)
- C. Tibia
- D. Mandible
Explanation: ***Clavicle*** - The **clavicle** is the **first bone to begin ossification** in the human body, starting around the **5th-6th week of gestation**. - It ossifies via **intramembranous ossification**, making it unique among long bones [1]. - This early ossification is a key landmark in fetal skeletal development and is consistently taught across medical curricula. *Mandible* - The **mandible** begins ossification around the **6th week of gestation**, shortly after the clavicle [1]. - While it is one of the earliest bones to ossify, it is **not the first**. - It also undergoes intramembranous ossification [1]. *Femur* - The **femur**, a long bone, begins ossification around the **7th-8th week of gestation** [1]. - It ossifies via **endochondral ossification**, which typically occurs later than intramembranous ossification [1]. *Tibia* - The **tibia** also begins ossification around the **7th-8th week of gestation**. - Like the femur, it follows the endochondral ossification pathway.
Question 55: The incudomalleolar joint is a?
- A. Saddle joint (Correct Answer)
- B. Pivot joint
- C. Ellipsoid joint
- D. Hinge joint
Explanation: ***Saddle joint*** - The **incudomalleolar joint** is classified as a **saddle joint** (also called a **sellar joint**), which is a type of synovial joint. - It has reciprocally concave-convex articular surfaces that fit together like a rider on a saddle. - This joint allows **slight gliding movements** between the head of the malleus and the body of the incus during sound transmission. - Standard anatomy texts including **Gray's Anatomy** classify this as a saddle joint based on its structural characteristics. *Pivot joint* - A **pivot joint** allows rotation around a single axis, such as the **atlantoaxial joint** (atlas rotating around the dens of axis) or the **proximal radioulnar joint**. - While the ossicular chain as a whole undergoes rotatory movement during sound transmission, the **incudomalleolar joint itself** is not classified as a pivot joint anatomically. *Ellipsoid joint* - An **ellipsoid joint** (condyloid joint) allows movement in two planes (flexion/extension and abduction/adduction) but restricts rotation. - Examples include the **radiocarpal joint** and **metacarpophalangeal joints** of the fingers. - The incudomalleolar joint has a different articular surface configuration. *Hinge joint* - A **hinge joint** permits movement primarily in one plane (flexion and extension), like a door hinge. - Examples include the **elbow joint**, **knee joint**, and **interphalangeal joints**. - This does not match the structural or functional characteristics of the incudomalleolar joint.
Question 56: Hilton's law primarily relates to which of the following?
- A. Nerve innervation only
- B. Nerve supply of joints, muscles moving them, and overlying skin (Correct Answer)
- C. Blood supply to joints
- D. None of the above
Explanation: ***Nerve supply of joints, muscles moving them, and overlying skin*** - **Hilton's law** states that the nerve supplying a joint also supplies the muscles that move the joint and the skin overlying the insertions of those muscles - This anatomical principle is clinically significant as it explains **referred pain patterns** from joints to surrounding structures - The law demonstrates the **functional integration** between joint innervation, muscle control, and cutaneous sensation *Nerve innervation only* - While Hilton's law involves nerve innervation, this option is too vague and incomplete - The law specifically describes the **relationship between three components**: joint nerves, muscle nerves, and cutaneous nerves - Simply stating "nerve innervation only" misses the **clinical significance** of the anatomical pattern *Blood supply to joints* - This refers to the vascular supply of joints (articular arteries), which is important for joint nutrition - However, **Hilton's law** specifically addresses **nerve supply patterns**, not vascular anatomy - Blood supply to joints follows different anatomical principles *None of the above* - This is incorrect because Hilton's law clearly relates to the integrated nerve supply pattern described in the correct option - The law is a fundamental principle in anatomy explaining the **functional relationship** between joint, muscle, and skin innervation
Question 57: Fossa ovalis is a remnant of -
- A. Septum primum (Correct Answer)
- B. Septum secundum
- C. Septum spurium
- D. AV cushion
Explanation: ***Septum primum*** - The **fossa ovalis** is a depression in the right atrium that represents the sealed-off foramen ovale [2]. - It is formed from the **septum primum**, which becomes the floor of the fossa ovalis. *Septum secundum* - The **septum secundum** forms the limbus or rim of the fossa ovalis, not the fossa itself. - This structure develops later than the septum primum and partially covers the foramen ovale during fetal development [2]. *Septum spurium* - The **septum spurium** is an embryonic ridge in the right atrium that typically regresses during development and does not contribute to the fossa ovalis. - It is a transient structure formed by the confluence of the right and left venous valves. *AV cushion* - The **atrioventricular (AV) cushions** contribute to the formation of the AV valves and the atrial and ventricular septa, but not directly to the fossa ovalis [1]. - They are crucial for separating the atria from the ventricles and forming the mitral and tricuspid valves.
Question 58: Nephron is derived from ?
- A. Ureteric bud
- B. Mesonephric duct
- C. Metanephros (Correct Answer)
- D. Mesonephros
Explanation: ***Metanephros*** - The **metanephric mesenchyme**, also known as the **metanephros**, gives rise to the excretory units of the kidney, which are the nephrons. - This mesenchymal tissue differentiates to form the **glomerulus**, Bowman's capsule, proximal and distal convoluted tubules, and the loop of Henle. *Ureteric bud* - The **ureteric bud** originates from the mesonephric duct and forms the collecting system of the kidney, including the ureter, renal pelvis, calyces, and collecting ducts. - It induces the differentiation of the metanephric mesenchyme but does not directly form the nephron itself. *Mesonephric duct* - The **mesonephric duct** (Wolffian duct) is a primitive embryonic structure that gives rise to the ureteric bud and parts of the male reproductive system. - It does not directly form any part of the nephron. *Mesonephros* - The **mesonephros** is a transient embryonic kidney that functions briefly during fetal development. - It degenerates and does not contribute to the formation of the definitive nephrons in the mature kidney.
Question 59: Fibrous stroma of liver is derived from -
- A. Endoderm from the foregut
- B. Endoderm from the midgut
- C. Endoderm from the hindgut
- D. Mesoderm from the septum transversum (Correct Answer)
Explanation: ***Mesoderm from the septum transversum*** - The **fibrous stroma of the liver**, which provides its structural framework, develops from the **mesoderm** of the **septum transversum** [1]. - The septum transversum is a thick mass of mesoderm that contributes to the formation of the **diaphragm** and the connective tissue elements of the liver [1]. *Endoderm from the foregut* - While the **parenchymal cells (hepatocytes)** of the liver are derived from the **endoderm of the foregut**, this tissue forms the functional units, not the fibrous supporting stroma. - The endoderm forms the glandular tissue, while the mesoderm forms the connective tissue [1]. *Endoderm from the midgut* - The midgut endoderm gives rise to structures like the **small intestine**, cecum, appendix, ascending colon, and part of the transverse colon, but not the liver's stroma [2]. - Its primary role is in forming the epithelial lining of these digestive organs. *Endoderm from the hindgut* - The hindgut endoderm develops into the distal third of the transverse colon, descending colon, sigmoid colon, rectum, and superior part of the anal canal, - It plays no role in the development of the liver's fibrous stroma.
Question 60: What structures are derived from the neural crest?
- A. Melanocytes
- B. Dental papillae
- C. Adrenal medulla
- D. All of the options (Correct Answer)
Explanation: ***All of the options*** - The **neural crest** is a multipotent, migratory cell population that contributes to the formation of many diverse tissues and organs during vertebrate development. - Neural crest cells give rise to a wide array of derivatives, including components of the nervous system, pigment cells, skeletal and connective tissues of the head and face, and endocrine glands [1]. *Melanocytes* - **Melanocytes**, the pigment-producing cells found in the skin, hair, eyes, and other tissues, are derived from the **neural crest** [2]. - These cells migrate extensively during development from the neural crest to their final destinations throughout the body. - Neural crest-derived melanocytes produce melanin, which provides pigmentation and protection against UV radiation [2]. *Dental papillae* - The **dental papilla** is crucial for tooth development and is formed from **ectomesenchymal cells** that are derived from the cranial neural crest. - These cells differentiate into the odontoblasts that produce dentin and also contribute to the pulp of the tooth. *Adrenal medulla* - The cells of the **adrenal medulla**, which produce catecholamines like epinephrine and norepinephrine, are specialized **postganglionic sympathetic neurons** derived from the neural crest. - They develop from neuroectodermal cells that migrate to the developing adrenal gland.