NIS India: Birth Doses - First Shield Up!
The National Immunization Schedule (NIS), part of India's Universal Immunization Programme (UIP), provides crucial early protection. At birth, infants receive:
- 📌 BOH at Birth:
- BCG (Bacillus Calmette-Guérin):
- Dose: 0.05ml if <1 month; 0.1ml if ≥1 month.
- Route: Intradermal (ID).
- Site: Left upper arm (deltoid).
- OPV-0 (Oral Polio Vaccine - Zero dose):
- Dose: 2 drops.
- Route: Oral.
- Hepatitis B - Birth dose (Hep B-0):
- Dose: 0.5ml.
- Route: Intramuscular (IM).
- Site: Anterolateral thigh.
- Timing: Within 24 hours of birth.
- BCG (Bacillus Calmette-Guérin):
⭐ BCG scar, a sign of successful vaccination, typically appears at 6-8 weeks post-vaccination.
Infant Primary Series (6,10,14wks) - Tiny Vax Titans
📌 Mnemonic: Poor Old Rats Prefer Fresh Ice! (Pentavalent, OPV, Rotavirus, PCV, fIPV)
The primary immunization series at 6, 10, and 14 weeks builds foundational immunity. Key vaccines include:
| Vaccine | Schedule (Weeks) | No. of Doses (Primary Series) | Dose Volume | Route & Site |
|---|---|---|---|---|
| bOPV (Bivalent Oral Polio Vaccine) | 6, 10, 14 | 3 | 2 drops | Oral |
| Pentavalent Vaccine (DPT+HepB+HiB) | 6, 10, 14 | 3 | 0.5ml | IM (Intramuscular), Anterolateral mid-thigh |
| Rotavirus Vaccine (RVV) | 6, 10, 14 | 3 | 5 drops / 2.5ml | Oral (Brand dependent volume) |
| PCV (Pneumococcal Conjugate Vaccine) | 6, 14 | 2 | 0.5ml | IM (Intramuscular), Anterolateral mid-thigh (alternate limb) |
| fIPV (Fractional Inactivated Polio Vaccine) | 6, 14 | 2 | 0.1ml | ID (Intradermal), Right upper arm |
⭐ Exam Favourite: The minimum interval recommended between doses of Pentavalent (or DTP, OPV, HepB, Hib, PCV, Rota) vaccines is 4 weeks.
Toddler & Child Boosters (9m-6y) - Mighty Immune March
- 9-12 Months:
- MR (Measles-Rubella): 1st dose, SC.
⭐ First dose of Measles-Rubella (MR) vaccine is given at 9-12 months of age.
- JE (Japanese Encephalitis): 1st dose, SC (endemic areas).
- Vitamin A: 1st dose (1 Lakh IU), Oral (with MR).
- MR (Measles-Rubella): 1st dose, SC.
- 16-24 Months: 📌 Mnemonic: "Mighty D.O.M. Jumps Again" (DPT, OPV, MR/MMR, JE, Vit A)
- MR/MMR: 2nd dose, SC.
- DPT: 1st Booster, IM.
- OPV: Booster, Oral.
- JE: 2nd dose, SC (endemic areas).
- Vitamin A: 2 Lakh IU, Oral (then every 6 months until 5 years).
- 5-6 Years:
- DPT: 2nd Booster, IM.
- Vitamin A: Continues (2 Lakh IU) every 6 months, Oral.
Adolescent & Maternal Shots - Guardian Doses
- Adolescent Immunization (Td Vaccine):
- Protects against Tetanus & Diphtheria.
- Schedule:
- Dose 1: At 10 years.
- Dose 2: At 16 years.
- Maternal Immunization (Pregnant Women - PW):
- Td Vaccine Schedule:
- Td-1: As early as possible in pregnancy.
- Td-2: 4 weeks after Td-1.
- Td-Booster: If PW received two Td doses in a pregnancy within the last 3 years.
⭐ For pregnant women, if previously immunized, one Td booster dose is sufficient.
- Other Recommended Vaccines for PW (if advised/available):
- Influenza (inactivated): Annually, any trimester.
- Tdap: One dose (27-36 weeks gestation) for neonatal pertussis protection.
- Td Vaccine Schedule:

High‑Yield Points - ⚡ Biggest Takeaways
- BCG, OPV-0, Hep B-0 are given at birth.
- Pentavalent vaccine (DPT, HepB, Hib) is administered at 6, 10, 14 weeks.
- Measles-Rubella (MR): 1st dose at 9-12 months, 2nd dose at 16-24 months.
- Inactivated Polio Vaccine (IPV): two fractional doses (fIPV) at 6 and 14 weeks.
- DPT boosters are given at 16-24 months and 5-6 years.
- Rotavirus vaccine (oral) is given at 6, 10, 14 weeks.
- Pneumococcal Conjugate Vaccine (PCV) at 6, 14 weeks and a booster at 9 months.
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