Voice Disorders

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Anatomy & Physiology - Voice Box Basics

  • Larynx (Voice Box): Airway protection; phonation.
    • Cartilages: Unpaired (Thyroid, Cricoid, Epiglottis); Paired (Arytenoids, Corniculates, Cuneiforms).
  • Vocal Cords:
    • True Vocal Cords (TVC): Mucosa, Reinke's space, vocalis m.; vibrate for voice.
    • False Vocal Cords (FVC): Superior to TVC; protective.
  • Nerve Supply:
    • Superior Laryngeal N. (SLN): Internal br. (sensory above TVC), External br. (motor to Cricothyroid - pitch control).
    • Recurrent Laryngeal N. (RLN): Motor to all other intrinsic muscles; sensory below TVC.

⭐ RLN supplies all intrinsic laryngeal muscles except Cricothyroid (by External SLN). Larynx Anatomy: Cartilages, Vocal Cords, Nerve Supply

Evaluation - Voice Detective Work

  • Patient History:
    • Onset, duration, progression, vocal load (occupation/habits)
    • Associated: Pain, dysphagia, reflux, cough, trauma
    • Lifestyle: Smoking, alcohol
  • Voice Assessment:
    • Subjective: Voice Handicap Index (VHI)
    • Perceptual: GRBAS scale (Grade, Roughness, Breathiness, Asthenia, Strain)
  • Laryngeal Examination:
    • Flexible Nasopharyngolaryngoscopy (NPL) or Rigid Laryngoscopy
    • Stroboscopy: Essential for mucosal wave, vibration.

    ⭐ Stroboscopy differentiates organic lesions (nodules, polyps affecting wave) from many functional dysphonias (often normal/hyperfunctional patterns).

  • Objective Analysis (if needed):
    • Acoustic: $F_0$, jitter, shimmer, Harmonics-to-Noise Ratio (HNR)
    • Aerodynamic: Airflow, phonation threshold pressure
  • Further Investigations (selected cases):
    • Imaging (CT/MRI): Suspected tumor, deep spread, paralysis cause
    • Laryngeal EMG: Vocal fold mobility disorders

Vocal fold mucosal wave in vibratory cycle

Benign Lesions & Inflammatory - Vocal Villains

  • Vocal Nodules (Singer's/Screamer's Nodules): Bilateral, symmetric, at junction of anterior 1/3 & middle 1/3 of true vocal cords (mid-membranous fold). Cause: chronic vocal abuse. Rx: voice rest, speech therapy; rarely surgery.
  • Vocal Polyps: Usually unilateral; can be sessile or pedunculated. Cause: vocal trauma, smoking, GERD. Rx: voice rest, microlaryngosurgery for persistent polyps.
  • Reinke's Edema (Polypoid Corditis): Diffuse, bilateral, floppy edema in Reinke's space (superficial lamina propria). Cause: SMOKING (classic), chronic vocal abuse, hypothyroidism. Voice: low-pitched, husky. Rx: smoking cessation, voice therapy, surgery if severe.

    ⭐ Reinke's Edema is strongly associated with smoking, especially in middle-aged women, leading to a characteristic deep, husky voice.

  • Vocal Cord Cysts: Unilateral, submucosal, intracordal; mucous retention or epidermoid. Rx: microlaryngosurgery.
  • Contact Ulcers/Granulomas: Posterior larynx, on medial surface of arytenoids. Cause: vocal abuse (e.g., hard glottal attack), GERD, intubation trauma. Rx: voice therapy, anti-reflux (PPIs), rarely surgery.
  • Laryngitis:
    • Acute: Viral most common. Sudden onset hoarseness. Rx: voice rest, hydration, steam inhalation.
    • Chronic: Due to irritants (smoking, pollution), GERD, chronic vocal abuse. Rx: eliminate cause, voice therapy. Vocal Nodules, Polyps, and Reinke's Edema

Neuro & Functional - Cord Control Chaos

  • Vocal Cord Palsy/Paralysis:
    • Etiology: Recurrent Laryngeal Nerve (RLN) injury (thyroidectomy, lung Ca, aortic aneurysm), CNS lesions.
    • Unilateral: Hoarseness, breathy voice, diplophonia. Cord positions: median, paramedian, lateral (cadaveric).
    • Bilateral:
      • Adductor (midline): Severe dyspnea, stridor. Airway emergency!
      • Abductor (lateral): Aphonia, aspiration.
    • 📌 RLN Vulnerability: Long course, esp. left RLN.
  • Spasmodic Dysphonia (SD): Task-specific focal laryngeal dystonia.
    • Adductor SD: Strained, choked voice breaks.
    • Abductor SD: Breathy, weak, whispered voice breaks.
    • Treatment: Botulinum toxin (Botox) injections.

    ⭐ Spasmodic Dysphonia is often misdiagnosed as MTD; laryngeal EMG can aid diagnosis.

  • Muscle Tension Dysphonia (MTD): Excessive perilaryngeal muscle activity.
    • Primary: No organic lesion. Secondary: Compensatory.
    • Voice: Strained, hoarse, vocal fatigue.
    • Treatment: Voice therapy.
  • Functional Aphonia/Dysphonia: Psychogenic; sudden onset, normal vegetative functions (cough, laugh).
    • Treatment: Voice therapy, psychological support.
  • Laryngeal Tremor: Rhythmic laryngeal muscle movements; often with essential tremor. Voice: quavering.

Vocal fold positions in paralysis

High‑Yield Points - ⚡ Biggest Takeaways

  • Hoarseness: primary symptom of laryngeal disease.
  • Laryngoscopy (indirect/flexible) is essential for diagnosis.
  • Vocal nodules: bilateral, voice abuse, junction of anterior 1/3 & posterior 2/3.
  • Vocal polyps: usually unilateral, from acute vocal trauma or smoking.
  • Reinke's edema: diffuse swelling, smoking-related, deep husky voice.
  • Persistent hoarseness >3 weeks in smokers: suspect laryngeal SCC.
  • Unilateral vocal cord palsy: breathy voice; bilateral: stridor risk.

Practice Questions: Voice Disorders

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To distinguish between cochlear and post-cochlear damage, which test is done?

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Flashcards: Voice Disorders

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The given lesion of the vocal cords is a laryngeal _____

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The given lesion of the vocal cords is a laryngeal _____

papilloma

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