Laryngomalacia

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Laryngomalacia - Floppy Larynx Intro

  • Definition: Congenital flaccidity of laryngeal tissues, leading to inward collapse during inspiration.
  • Also known as "floppy larynx".
  • Most common congenital laryngeal anomaly (60-75% of cases).
  • Results in intermittent, partial airway obstruction.

Normal vs. Laryngomalacia Types I, II, III

⭐ Laryngomalacia is the most common cause of stridor in infants and newborns.

  • Typically presents in the first few weeks of life.
  • Stridor is usually inspiratory, worse when supine, agitated, or feeding.

Pathophysiology - Why So Wobbly?

  • Immature, floppy laryngeal cartilages (epiglottis, arytenoids) leading to ↑ collapsibility.

  • Redundant supraglottic soft tissues (e.g., aryepiglottic folds, arytenoid mucosa).

  • Possible neuromuscular incoordination or hypotonia affecting laryngeal support.

  • During inspiration, negative intrathoracic pressure causes these lax supraglottic structures to prolapse inward, obstructing the airway.

  • This dynamic collapse leads to turbulent airflow and characteristic inspiratory stridor.

  • Common patterns of collapse:

    • Type 1: Inward collapse of arytenoid cartilages and redundant mucosa (most common).
    • Type 2: Shortened aryepiglottic folds pulling epiglottis posteroinferiorly.
    • Type 3: Posterior and/or lateral collapse of an elongated, omega-shaped epiglottis.

⭐ Laryngomalacia is the most common congenital laryngeal anomaly and cause of stridor in infants; symptoms typically worsen with agitation, feeding, or supine positioning due to increased inspiratory effort and gravitational effects on floppy tissues.

Clinical Signs - Noisy Breather Baby

  • Onset: Typically within first 2 weeks of life, often by 4-6 weeks.
  • Stridor:
    • Predominantly inspiratory, high-pitched, fluttering.
    • Intermittent; worsens with supine position, agitation, feeding, URIs.
    • Improves with prone position or neck extension.
  • Voice & Cry: Usually normal.
  • Feeding: Generally unaffected; severe cases may show poor weight gain, choking.
  • Course: Symptoms peak around ~6 months, typically resolve by 18-24 months.

⭐ Stridor in laryngomalacia is classically inspiratory and characteristically worsens in the supine position and with agitation.

Diagnosis - Scope The Larynx

  • Gold Standard: Flexible Fiberoptic Laryngoscopy (FFL).
    • Performed on an awake, spontaneously breathing child.
    • Allows direct visualization of dynamic laryngeal collapse during inspiration.
  • Key Findings (Inspiratory Supraglottic Collapse):
    • Type 1: Inward collapse of arytenoid cartilages/redundant mucosa.
    • Type 2: Medial collapse of short aryepiglottic folds.
    • Type 3: Posterior and inferior collapse of an omega-shaped (Ω) epiglottis. Laryngomalacia Classification Types

⭐ Laryngomalacia is the most common congenital laryngeal anomaly and the primary cause of stridor in infants.

Management - Fixing The Flop

  • Conservative (Most cases: 90%):
    • Observation, reassurance.
    • Positioning: Prone or upright after feeds.
    • Feeding modification: Small, frequent, thickened feeds.
  • Medical:
    • Anti-reflux (PPIs, H2 blockers) if GERD suspected.
  • Surgical (Severe cases: 10-20%): Aryepiglottoplasty / Supraglottoplasty.
    • Indications: Failure to thrive (FTT), severe dyspnea, cyanosis, apneas, cor pulmonale, feeding difficulties.

⭐ Supraglottoplasty is the gold standard surgical treatment for severe laryngomalacia, involving trimming of redundant aryepiglottic folds or arytenoid mucosa.

High‑Yield Points - ⚡ Biggest Takeaways

  • Laryngomalacia: most common congenital laryngeal anomaly and cause of stridor in infants.
  • Inspiratory stridor is characteristic, worsening with crying, feeding, supine position; improves when prone.
  • Diagnosis via flexible fiberoptic laryngoscopy (FFL), showing an omega-shaped epiglottis or arytenoid prolapse.
  • Typically benign and self-resolves by 18-24 months.
  • Management: Observation for mild cases; supraglottoplasty for severe symptoms like failure to thrive (FTT) or apnea.
  • Frequently associated with Gastroesophageal Reflux Disease (GERD).

Practice Questions: Laryngomalacia

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2 months old child having birth weight 2kg, with poor feeding, very sleepy and wheezing. The diagnosis is?

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Flashcards: Laryngomalacia

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Routine indications for a _____ tracheostomy is Laryngo-tracheal stenosis, Juvenile onset respiratory papillomatosis and Crush injury to larynx.

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Routine indications for a _____ tracheostomy is Laryngo-tracheal stenosis, Juvenile onset respiratory papillomatosis and Crush injury to larynx.

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