Neurobiology of addiction — Flashcards

Flashcard 1: Neuro/PsychDo benzodiazepines have addictive potential? _____

Answer: Yes

Flashcard 2: Non-specific symptoms of _____ withdrawal (stimulant or depressant) include post-use "crash", depression, lethargy, and hypersomnia/weight gain

Answer: stimulant

Flashcard 3: D2 dopamine receptors are primarily found in the _____ (organ system)

Answer: CNS

Flashcard 4: Which dopaminergic pathway is the primary target for the antipsychotic treatment of schizophrenia?

Answer: Mesolimbic pathway

Flashcard 5: What symptoms of alcohol withdrawal occur during the 3 - 36 hour time period?

Answer: Minor withdrawal symptoms (e.g., tremulousness, anxiety, insomnia, GI upset) and potentially withdrawal seizures.

Extra: **Alcohol Withdrawal Timeline:** - **6-24 hours:** Minor symptoms (anxiety, insomnia, tremors, palpitations, GI upset). - **6-48 hours:** Withdrawal seizures (generalized tonic-clonic). - **12-48 hours:** Alcoholic hallucinosis (stable vitals). - **48-96 hours:** Delirium tremens (altered mental status, autonomic instability).

Flashcard 6: What emotional states are most associated with the nucleus accumbens?

Answer: reward, pleasure, addiction, fear mnemonic: accumulated rewards