Schizophrenia — Flashcards

_____ = ↓ suicide risk in schizophrenia

Hint: Atypical antipsychotic

What dopaminergic pathway abnormalities are theorized to be responsible for the positive and negative symptoms of schizophrenia? Positive symptoms: _____ Negative symptoms: _____

Acute and late onset schizophrenia = _____ prognosis

Hint: good/poor

What is the dopamine hypothesis of the etiology of schizophrenia? _____

The DSM-5 criteria for schizophrenia include: A. At least two of the following symptoms (at least one must be 1, 2, or 3), each present for a significant portion of time during a one-month period: 1. _____ 2. _____ 3. _____ 4. Disorganized or catatonic behavior 5. Negative symptoms B. Significant impairment in social or occupational functioning C. Continuous signs of the disturbance persist for ≥ 6 months *May include periods of prodromal or residual symptoms D./E. Not better explained by another mental disorder, medical condition, or substance F. If there is a history of autism spectrum disorder, diagnosis of schizophrenia is made only if prominent delusions or hallucinations

Favorable prognostic factors in schizophrenia include acute onset, identifiable precipitant, older age at onset, and predominantly _____ psychotic symptoms

Lifetime prevalence of schizophrenia ≈ _____

Hint: %

Blockage of the mesocortical dopamine pathway results in increased _____" symptoms of schizophrenia.

First generation (typical) antipsychotics treat _____ symptoms of schizophrenia Second generation (atypical) antipsychotics treat _____ symptoms of schizophrenia

_____ = ↓ suicide risk in schizophrenia

Hint: Atypical antipsychotic